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Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare.
Marx U, Beken S, Chen Z, Dehne EM, Doherty A, Ewart L, Fitzpatrick SC, Griffith LG, Gu Z, Hartung T, Hickman J, Ingber DE, Ishida S, Jeong J, Leist M, Levin L, Mendrick DL, Pallocca G, Platz S, Raschke M, Smirnova L, Tagle DA, Trapecar M, van Balkom BWM, van den Eijnden-van Raaij J, van der Meer A, Roth A. Marx U, et al. Among authors: ingber de. ALTEX. 2025 Jan 17. doi: 10.14573/altex.2410112. Online ahead of print. ALTEX. 2025. PMID: 39827406
Inflammatory Bowel Disease Drivers Revealed in Human Organ Chips.
Özkan A, Merry G, Chou DB, Posey RR, Stejskalova A, Calderon K, Sperry M, Horvath V, Ferri LE, Carlotti E, McDonald SAC, Winton DJ, Riccardi R, Bordeianou L, Hall S, Goyal G, Ingber DE. Özkan A, et al. Among authors: ingber de. medRxiv [Preprint]. 2024 Dec 8:2024.12.05.24318563. doi: 10.1101/2024.12.05.24318563. medRxiv. 2024. PMID: 39677416 Free PMC article. Preprint.
Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation.
Sperry MM, Charrez B, Fotowat H, Gardner E, Pilobello K, Izadifar Z, Lin T, Kuelker A, Kaki S, Lewandowski M, Lightbown S, Martinez R, Marquez S, Moore J, Plaza-Oliver M, Sesay AM, Shcherbina K, Sheehan K, Takeda T, Del Campo D, Andrijauskaite K, Cisneros E, Lopez R, Cano I, Maxwell Z, Jessop I, Veraza R, Bunegin L, Percival TJ, Yracheta J, Pena JJ, Wood DM, Homas ZT, Hinshaw CJ, Cox-Hinshaw J, Parry OG, Sleeter JJ, Weitzel EK, Levin M, Super M, Novak R, Ingber DE. Sperry MM, et al. Among authors: ingber de. Elife. 2024 Sep 24;13:RP93796. doi: 10.7554/eLife.93796. Elife. 2024. PMID: 39316042 Free PMC article.
Organ chips with integrated multifunctional sensors enable continuous metabolic monitoring at controlled oxygen levels.
Izadifar Z, Charrez B, Almeida M, Robben S, Pilobello K, van der Graaf-Mas J, Marquez SL, Ferrante TC, Shcherbina K, Gould R, LoGrande NT, Sesay AM, Ingber DE. Izadifar Z, et al. Among authors: ingber de. Biosens Bioelectron. 2024 Dec 1;265:116683. doi: 10.1016/j.bios.2024.116683. Epub 2024 Aug 17. Biosens Bioelectron. 2024. PMID: 39213819 Free PMC article.
Intestinal organ chips for disease modelling and personalized medicine.
Özkan A, LoGrande NT, Feitor JF, Goyal G, Ingber DE. Özkan A, et al. Among authors: ingber de. Nat Rev Gastroenterol Hepatol. 2024 Nov;21(11):751-773. doi: 10.1038/s41575-024-00968-3. Epub 2024 Aug 27. Nat Rev Gastroenterol Hepatol. 2024. PMID: 39192055 Review.
Donepezil Nanoemulsion Induces a Torpor-like State with Reduced Toxicity in Nonhibernating Xenopus laevis Tadpoles.
Plaza Oliver M, Gardner E, Lin T, Sheehan K, Sperry MM, Lightbown S, Martínez MR, Del Campo D, Fotowat H, Lewandowski M, Takeda T, C Pauer A, Kaushal S, Gnyawali V, Lozano MV, Santander Ortega MJ, Novak R, Super M, Ingber DE. Plaza Oliver M, et al. Among authors: ingber de. ACS Nano. 2024 Sep 3;18(35):23991-24003. doi: 10.1021/acsnano.4c02012. Epub 2024 Aug 21. ACS Nano. 2024. PMID: 39167921 Free PMC article.
442 results