Zhang J - Search Results

1

An orally active corticotropin releasing factor 1 receptor antagonist from 8-aryl-1,3a,7,8-tetraaza-cyclopenta[a]indenes.

Han X, Civiello R, Pin SS, Burris K, Balanda LA, Knipe J, Ren S, Fiedler T, Browman KE, Macci R, Taber MT, Zhang J, Dubowchik GM. Han X, et al. Among authors: zhang j. Bioorg Med Chem Lett. 2007 Apr 1;17(7):2026-30. doi: 10.1016/j.bmcl.2007.01.008. Epub 2007 Jan 13. Bioorg Med Chem Lett. 2007. PMID: 17258456

2

Design, synthesis and SAR of a series of 2-substituted 4-amino-quinazoline neuropeptide Y Y5 receptor antagonists.

Rueeger H, Rigollier P, Yamaguchi Y, Schmidlin T, Schilling W, Criscione L, Whitebread S, Chiesi M, Walker MW, Dhanoa D, Islam I, Zhang J, Gluchowski C. Rueeger H, et al. Among authors: zhang j. Bioorg Med Chem Lett. 2000 Jun 5;10(11):1175-9. doi: 10.1016/s0960-894x(00)00177-3. Bioorg Med Chem Lett. 2000. PMID: 10866375

3

Nonpeptide endothelin antagonists: from lower affinity pyrazol-5-ols to higher affinity pyrazole-5-carboxylic acids.

Zhang J, Didierlaurent S, Fortin M, Lefrançois D, Uridat E, Vevert JP. Zhang J, et al. Bioorg Med Chem Lett. 2000 Jun 19;10(12):1351-5. doi: 10.1016/s0960-894x(00)00232-8. Bioorg Med Chem Lett. 2000. PMID: 10890162

4

Potent nonpeptide endothelin antagonists: synthesis and structure-activity relationships of pyrazole-5-carboxylic acids.

Zhang J, Didierlaurent S, Fortin M, Lefrançois D, Uridat E, Vevert JP. Zhang J, et al. Bioorg Med Chem Lett. 2000 Nov 20;10(22):2575-8. doi: 10.1016/s0960-894x(00)00513-8. Bioorg Med Chem Lett. 2000. PMID: 11086733

5

2-arylaminothiazoles as high-affinity corticotropin-releasing factor 1 receptor (CRF1R) antagonists: synthesis, binding studies and behavioral efficacy.

Dubowchik GM, Michne JA, Zuev D, Schwartz W, Scola PM, James CA, Ruediger EH, Pin SS, Burris KD, Balanda LA, Gao Q, Wu D, Fung L, Fiedler T, Browman KE, Taber MT, Zhang J. Dubowchik GM, et al. Among authors: zhang j. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3997-4000. doi: 10.1016/j.bmcl.2003.08.055. Bioorg Med Chem Lett. 2003. PMID: 14592493

6

Optimization of CRF1R binding affinity of 2-(2,4,6-trichlorophenyl)-4-trifluoromethyl-5-aminomethylthiazoles through rapid and selective parallel synthesis.

Zuev D, Michne JA, Pin SS, Zhang J, Taber MT, Dubowchik GM. Zuev D, et al. Among authors: zhang j. Bioorg Med Chem Lett. 2005 Jan 17;15(2):431-4. doi: 10.1016/j.bmcl.2004.10.055. Bioorg Med Chem Lett. 2005. PMID: 15603967

7

Synthesis and structure-activity relationship of imidazo[1,2-a]benzimidazoles as corticotropin-releasing factor 1 receptor antagonists.

Han X, Pin SS, Burris K, Fung LK, Huang S, Taber MT, Zhang J, Dubowchik GM. Han X, et al. Among authors: zhang j. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4029-32. doi: 10.1016/j.bmcl.2005.06.028. Bioorg Med Chem Lett. 2005. PMID: 15982881

8

Synthesis, structure-activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists.

Han X, Michne JA, Pin SS, Burris KD, Balanda LA, Fung LK, Fiedler T, Browman KE, Taber MT, Zhang J, Dubowchik GM. Han X, et al. Among authors: zhang j. Bioorg Med Chem Lett. 2005 Sep 1;15(17):3870-3. doi: 10.1016/j.bmcl.2005.05.117. Bioorg Med Chem Lett. 2005. PMID: 15990298

9

Design, synthesis and evaluation of constrained tetrahydroimidazopyrimidine derivatives as antagonists of corticotropin-releasing factor type 1 receptor (CRF1R).

Vrudhula VM, Dasgupta B, Pin SS, Burris KD, Balanda LA, Fung LK, Fiedler T, Browman KE, Taber MT, Zhang J, Macor JE, Dubowchik GM. Vrudhula VM, et al. Among authors: zhang j. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1905-9. doi: 10.1016/j.bmcl.2010.01.127. Epub 2010 Feb 4. Bioorg Med Chem Lett. 2010. PMID: 20185312

10

Discovery of 6-chloro-2-trifluoromethyl-7-aryl-7H-imidazo[1,2-a]imidazol-3-ylmethylamines, a novel class of corticotropin-releasing factor receptor type 1 (CRF1R) antagonists.

Zuev D, Vrudhula VM, Michne JA, Dasgupta B, Pin SS, Huang XS, Wu D, Gao Q, Zhang J, Taber MT, Macor JE, Dubowchik GM. Zuev D, et al. Among authors: zhang j. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3669-74. doi: 10.1016/j.bmcl.2010.04.094. Epub 2010 Apr 24. Bioorg Med Chem Lett. 2010. PMID: 20471832

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

178,604 results

Search Page

Filters