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Augmenting TCR signal strength and ICOS costimulation results in metabolically fit and therapeutically potent human CAR Th17 cells.
Wyatt MM, Huff LW, Nelson MH, Neal LR, Medvec AR, Rangel Rivera GO, Smith AS, Rivera Reyes AM, Knochelmann HM, Riley JL, Lesinski GB, Paulos CM. Wyatt MM, et al. Among authors: paulos cm. Mol Ther. 2023 Jul 5;31(7):2120-2131. doi: 10.1016/j.ymthe.2023.04.010. Epub 2023 Apr 20. Mol Ther. 2023. PMID: 37081789 Free PMC article.
Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell- and CXCR3-dependent manner.
Ware MB, Phillips M, McQuinn C, Zaidi MY, Knochelmann HM, Greene E, Robinson B, Herting CJ, Mace TA, Chen Z, Zhang C, Farren MR, Ruggieri AN, Bowers JS, Shakya R, Farris AB, Young G, Carson WE 3rd, El-Rayes B, Paulos CM, Lesinski GB. Ware MB, et al. Among authors: paulos cm. JCI Insight. 2023 Apr 24;8(8):e155006. doi: 10.1172/jci.insight.155006. JCI Insight. 2023. PMID: 36881480 Free PMC article.
Interleukin-2-dependent mechanisms of tolerance and immunity in vivo.
Antony PA, Paulos CM, Ahmadzadeh M, Akpinarli A, Palmer DC, Sato N, Kaiser A, Hinrichs CS, Klebanoff CA, Tagaya Y, Restifo NP. Antony PA, et al. Among authors: paulos cm. J Immunol. 2006 May 1;176(9):5255-66. doi: 10.4049/jimmunol.176.9.5255. J Immunol. 2006. PMID: 16621991 Free PMC article.
Toll-like receptors in tumor immunotherapy.
Paulos CM, Kaiser A, Wrzesinski C, Hinrichs CS, Cassard L, Boni A, Muranski P, Sanchez-Perez L, Palmer DC, Yu Z, Antony PA, Gattinoni L, Rosenberg SA, Restifo NP. Paulos CM, et al. Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5280-9. doi: 10.1158/1078-0432.CCR-07-1378. Clin Cancer Res. 2007. PMID: 17875756 Free PMC article. Review.
117 results