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The role of calcium influx in cellular proliferation induced by interaction of endogenous ganglioside GM1 with the B subunit of cholera toxin.
Buckley NE, Su Y, Milstien S, Spiegel S. Buckley NE, et al. Among authors: spiegel s. Biochim Biophys Acta. 1995 Jun 6;1256(3):275-83. doi: 10.1016/0005-2760(95)00030-g. Biochim Biophys Acta. 1995. PMID: 7786888 Free article.
It was previously shown that the B subunit had no effect on cAMP, protein kinase C or phosphoinositide turnover, but did cause an increase in the influx of calcium from extracellular sources (Spiegel, S. and Panagiotopoulos, C. (1988) Exp. Cell Res. 177, 414-427). I …
It was previously shown that the B subunit had no effect on cAMP, protein kinase C or phosphoinositide turnover, but did cause an increase i …
Sphingoid bases and phospholipase D activation.
Spiegel S, Milstien S. Spiegel S, et al. Chem Phys Lipids. 1996 May 24;80(1-2):27-36. doi: 10.1016/0009-3084(96)02543-1. Chem Phys Lipids. 1996. PMID: 8681426 Free article. Review.
Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis.
Wang F, Van Brocklyn JR, Hobson JP, Movafagh S, Zukowska-Grojec Z, Milstien S, Spiegel S. Wang F, et al. Among authors: spiegel s. J Biol Chem. 1999 Dec 10;274(50):35343-50. doi: 10.1074/jbc.274.50.35343. J Biol Chem. 1999. PMID: 10585401 Free article.
In agreement with previous findings in human breast cancer cells (Wang, F., Nohara, K., Olivera, O., Thompson, E. W., and Spiegel, S. (1999) Exp. Cell Res. 247, 17-28), SPP, at micromolar concentrations, inhibited chemotaxis of both vector- and EDG-1-overexpressing …
In agreement with previous findings in human breast cancer cells (Wang, F., Nohara, K., Olivera, O., Thompson, E. W., and Spiegel, …
Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform.
Liu H, Sugiura M, Nava VE, Edsall LC, Kono K, Poulton S, Milstien S, Kohama T, Spiegel S. Liu H, et al. Among authors: spiegel s. J Biol Chem. 2000 Jun 30;275(26):19513-20. doi: 10.1074/jbc.M002759200. J Biol Chem. 2000. PMID: 10751414 Free article.
Based on sequence homology to murine and human sphingosine kinase-1 (SPHK1), which we recently cloned (Kohama, T., Oliver, A., Edsall, L. , Nagiec, M. M., Dickson, R., and Spiegel, S. (1998) J. Biol. Chem. 273, 23722-23728), we have now cloned a second type of mouse …
Based on sequence homology to murine and human sphingosine kinase-1 (SPHK1), which we recently cloned (Kohama, T., Oliver, A., Edsall, L. , …
Functions of a new family of sphingosine-1-phosphate receptors.
Spiegel S, Milstien S. Spiegel S, et al. Biochim Biophys Acta. 2000 Apr 12;1484(2-3):107-16. doi: 10.1016/s1388-1981(00)00010-x. Biochim Biophys Acta. 2000. PMID: 10760461 Free article. Review. No abstract available.
498 results