Pastan IH - Search Results

1

The multichain interleukin-2 receptor: a target for immunotherapy.

Waldmann TA, Pastan IH, Gansow OA, Junghans RP. Waldmann TA, et al. Among authors: pastan ih. Ann Intern Med. 1992 Jan 15;116(2):148-60. doi: 10.7326/0003-4819-116-2-148. Ann Intern Med. 1992. PMID: 1727619 Review.

2

Recombinant toxins: new therapeutic agents for cancer.

Pastan IH, Pai LH, Brinkmann U, Fitzgerald DJ. Pastan IH, et al. Ann N Y Acad Sci. 1995 Jun 30;758:345-54. doi: 10.1111/j.1749-6632.1995.tb24840.x. Ann N Y Acad Sci. 1995. PMID: 7625703 Review. No abstract available.

3

Recombinant immunotoxins: new therapeutic agents for cancer treatment.

Pastan IH. Pastan IH. Cancer Detect Prev. 1993;17(2):289-93. Cancer Detect Prev. 1993. PMID: 8402714

4

Radioimmunotherapy of A431 xenografted mice with pretargeted B3 antibody-streptavidin and (90)Y-labeled 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid (DOTA)-biotin.

Yao Z, Zhang M, Axworthy DB, Wong KJ, Garmestani K, Park L, Park CW, Mallett RW, Theodore LJ, Yau EK, Waldmann TA, Brechbiel MW, Paik CH, Pastan I, Carrasquillo JA. Yao Z, et al. Cancer Res. 2002 Oct 15;62(20):5755-60. Cancer Res. 2002. PMID: 12384535

5

Pretargeted alpha emitting radioimmunotherapy using (213)Bi 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid-biotin.

Yao Z, Zhang M, Garmestani K, Axworthy DB, Mallett RW, Fritzberg AR, Theodore LJ, Plascjak PS, Eckelman WC, Waldmann TA, Pastan I, Paik CH, Brechbiel MW, Carrasquillo JA. Yao Z, et al. Clin Cancer Res. 2004 May 1;10(9):3137-46. doi: 10.1158/1078-0432.ccr-03-0171. Clin Cancer Res. 2004. PMID: 15131055

6

New immunotoxins targeting CD123, a stem cell antigen on acute myeloid leukemia cells.

Du X, Ho M, Pastan I. Du X, et al. J Immunother. 2007 Sep;30(6):607-13. doi: 10.1097/CJI.0b013e318053ed8e. J Immunother. 2007. PMID: 17667524

7

An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes.

Onda M, Beers R, Xiang L, Nagata S, Wang QC, Pastan I. Onda M, et al. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11311-6. doi: 10.1073/pnas.0804851105. Epub 2008 Aug 4. Proc Natl Acad Sci U S A. 2008. PMID: 18678888 Free PMC article.

8

A recombinant immunotoxin targeting CD22 with low immunogenicity, low nonspecific toxicity, and high antitumor activity in mice.

Hansen JK, Weldon JE, Xiang L, Beers R, Onda M, Pastan I. Hansen JK, et al. J Immunother. 2010 Apr;33(3):297-304. doi: 10.1097/CJI.0b013e3181cd1164. J Immunother. 2010. PMID: 20445350 Free PMC article.

9

A recombinant immunotoxin engineered for increased stability by adding a disulfide bond has decreased immunogenicity.

Liu W, Onda M, Kim C, Xiang L, Weldon JE, Lee B, Pastan I. Liu W, et al. Protein Eng Des Sel. 2012 Jan;25(1):1-6. doi: 10.1093/protein/gzr053. Epub 2011 Nov 17. Protein Eng Des Sel. 2012. PMID: 22101015 Free PMC article.

10

Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A.

Mazor R, Vassall AN, Eberle JA, Beers R, Weldon JE, Venzon DJ, Tsang KY, Benhar I, Pastan I. Mazor R, et al. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):E3597-603. doi: 10.1073/pnas.1218138109. Epub 2012 Dec 3. Proc Natl Acad Sci U S A. 2012. PMID: 23213206 Free PMC article.

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