Kershaw NJ - Search Results

1

Clavulanic acid dehydrogenase: structural and biochemical analysis of the final step in the biosynthesis of the beta-lactamase inhibitor clavulanic acid.

MacKenzie AK, Kershaw NJ, Hernandez H, Robinson CV, Schofield CJ, Andersson I. MacKenzie AK, et al. Among authors: kershaw nj. Biochemistry. 2007 Feb 13;46(6):1523-33. doi: 10.1021/bi061978x. Epub 2007 Jan 19. Biochemistry. 2007. PMID: 17279617

2

ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity.

Kershaw NJ, McNaughton HJ, Hewitson KS, Hernández H, Griffin J, Hughes C, Greaves P, Barton B, Robinson CV, Schofield CJ. Kershaw NJ, et al. Eur J Biochem. 2002 Apr;269(8):2052-9. doi: 10.1046/j.1432-1033.2002.02853.x. Eur J Biochem. 2002. PMID: 11985581 Free article.

3

Crystal structures of an oligopeptide-binding protein from the biosynthetic pathway of the beta-lactamase inhibitor clavulanic acid.

Mackenzie AK, Valegård K, Iqbal A, Caines ME, Kershaw NJ, Jensen SE, Schofield CJ, Andersson I. Mackenzie AK, et al. Among authors: kershaw nj. J Mol Biol. 2010 Feb 19;396(2):332-44. doi: 10.1016/j.jmb.2009.11.045. Epub 2009 Nov 24. J Mol Biol. 2010. PMID: 19941870

4

Structural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathway.

Valegård K, Iqbal A, Kershaw NJ, Ivison D, Généreux C, Dubus A, Blikstad C, Demetriades M, Hopkinson RJ, Lloyd AJ, Roper DI, Schofield CJ, Andersson I, McDonough MA. Valegård K, et al. Among authors: kershaw nj. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1567-79. doi: 10.1107/S0907444913011013. Epub 2013 Jul 20. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23897479

5

X-ray crystal structure of ornithine acetyltransferase from the clavulanic acid biosynthesis gene cluster.

Elkins JM, Kershaw NJ, Schofield CJ. Elkins JM, et al. Among authors: kershaw nj. Biochem J. 2005 Jan 15;385(Pt 2):565-73. doi: 10.1042/BJ20040814. Biochem J. 2005. PMID: 15352873 Free PMC article.

6

ORF17 from the clavulanic acid biosynthesis gene cluster catalyzes the ATP-dependent formation of N-glycyl-clavaminic acid.

Arulanantham H, Kershaw NJ, Hewitson KS, Hughes CE, Thirkettle JE, Schofield CJ. Arulanantham H, et al. Among authors: kershaw nj. J Biol Chem. 2006 Jan 6;281(1):279-87. doi: 10.1074/jbc.M507711200. Epub 2005 Oct 26. J Biol Chem. 2006. PMID: 16251194 Free article.

7

Structural studies on 2-oxoglutarate oxygenases and related double-stranded beta-helix fold proteins.

Clifton IJ, McDonough MA, Ehrismann D, Kershaw NJ, Granatino N, Schofield CJ. Clifton IJ, et al. Among authors: kershaw nj. J Inorg Biochem. 2006 Apr;100(4):644-69. doi: 10.1016/j.jinorgbio.2006.01.024. Epub 2006 Mar 2. J Inorg Biochem. 2006. PMID: 16513174 Review.

8

The enzymology of clavam and carbapenem biosynthesis.

Kershaw NJ, Caines ME, Sleeman MC, Schofield CJ. Kershaw NJ, et al. Chem Commun (Camb). 2005 Sep 14;(34):4251-63. doi: 10.1039/b505964j. Epub 2005 Aug 8. Chem Commun (Camb). 2005. PMID: 16113715

9

Crystallographic and mass spectrometric analyses of a tandem GNAT protein from the clavulanic acid biosynthesis pathway.

Iqbal A, Arunlanantham H, Brown T Jr, Chowdhury R, Clifton IJ, Kershaw NJ, Hewitson KS, McDonough MA, Schofield CJ. Iqbal A, et al. Among authors: kershaw nj. Proteins. 2010 May 1;78(6):1398-407. doi: 10.1002/prot.22653. Proteins. 2010. PMID: 20014241

10

Structure-function analysis of phytanoyl-CoA 2-hydroxylase mutations causing Refsum's disease.

Mukherji M, Chien W, Kershaw NJ, Clifton IJ, Schofield CJ, Wierzbicki AS, Lloyd MD. Mukherji M, et al. Among authors: kershaw nj. Hum Mol Genet. 2001 Sep 1;10(18):1971-82. doi: 10.1093/hmg/10.18.1971. Hum Mol Genet. 2001. PMID: 11555634

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