Singh LR - Search Results

1

Guanidinium chloride and urea denaturations of beta-lactoglobulin A at pH 2.0 and 25 degrees C: the equilibrium intermediate contains non-native structures (helix, tryptophan and hydrophobic patches).

Dar TA, Singh LR, Islam A, Anjum F, Moosavi-Movahedi AA, Ahmad F. Dar TA, et al. Among authors: singh lr. Biophys Chem. 2007 May;127(3):140-8. doi: 10.1016/j.bpc.2007.01.006. Epub 2007 Jan 25. Biophys Chem. 2007. PMID: 17289254

2

Testing the paradigm that the denaturing effect of urea on protein stability is offset by methylamines at the physiological concentration ratio of 2:1 (urea:methylamines).

Singh LR, Ali Dar T, Haque I, Anjum F, Moosavi-Movahedi AA, Ahmad F. Singh LR, et al. Biochim Biophys Acta. 2007 Dec;1774(12):1555-62. doi: 10.1016/j.bbapap.2007.09.006. Epub 2007 Sep 26. Biochim Biophys Acta. 2007. PMID: 17962089

3

Glycine betaine may have opposite effects on protein stability at high and low pH values.

Singh LR, Dar TA, Rahman S, Jamal S, Ahmad F. Singh LR, et al. Biochim Biophys Acta. 2009 Jun;1794(6):929-35. doi: 10.1016/j.bbapap.2009.02.005. Epub 2009 Feb 28. Biochim Biophys Acta. 2009. PMID: 19254782

4

Living with urea stress.

Singh LR, Dar TA, Ahmad F. Singh LR, et al. J Biosci. 2009 Jun;34(2):321-31. doi: 10.1007/s12038-009-0036-0. J Biosci. 2009. PMID: 19550048 Review.

5

Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes.

Jamal S, Poddar NK, Singh LR, Dar TA, Rishi V, Ahmad F. Jamal S, et al. Among authors: singh lr. FEBS J. 2009 Oct;276(20):6024-32. doi: 10.1111/j.1742-4658.2009.07317.x. Epub 2009 Sep 17. FEBS J. 2009. PMID: 19765077 Free article.

6

Protein and DNA destabilization by osmolytes: the other side of the coin.

Singh LR, Poddar NK, Dar TA, Kumar R, Ahmad F. Singh LR, et al. Life Sci. 2011 Jan 17;88(3-4):117-25. doi: 10.1016/j.lfs.2010.10.020. Epub 2010 Nov 1. Life Sci. 2011. PMID: 21047521 Review.

7

Why is glycine not a part of the osmoticum in the urea-rich cells?

Khan S, Bano Z, Singh LR, Hassan MI, Islam A, Ahmad F. Khan S, et al. Among authors: singh lr. Protein Pept Lett. 2013 Jan;20(1):61-70. Protein Pept Lett. 2013. PMID: 22670764

8

Testing the ability of non-methylamine osmolytes present in kidney cells to counteract the deleterious effects of urea on structure, stability and function of proteins.

Khan S, Bano Z, Singh LR, Hassan MI, Islam A, Ahmad F. Khan S, et al. Among authors: singh lr. PLoS One. 2013 Sep 9;8(9):e72533. doi: 10.1371/journal.pone.0072533. eCollection 2013. PLoS One. 2013. PMID: 24039776 Free PMC article.

9

Ignored avenues in alpha-synuclein associated proteopathy.

Chowhan RK, Mittal S, Dar TA, Kamal MA, Singh LR. Chowhan RK, et al. Among authors: singh lr. CNS Neurol Disord Drug Targets. 2014;13(7):1246-57. doi: 10.2174/1871527313666140917121943. CNS Neurol Disord Drug Targets. 2014. PMID: 25230221 Review.

10

Structural characteristic of the initial unfolded state on refolding determines catalytic efficiency of the folded protein in presence of osmolytes.

Warepam M, Sharma GS, Dar TA, Khan MK, Singh LR. Warepam M, et al. Among authors: singh lr. PLoS One. 2014 Oct 14;9(10):e109408. doi: 10.1371/journal.pone.0109408. eCollection 2014. PLoS One. 2014. PMID: 25313668 Free PMC article.

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