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Machine learning analysis of the orbitofrontal cortex transcriptome of human opioid users identifies Shisa7 as a translational target relevant for heroin-seeking leveraging a male rat model.
Ellis RJ, Ferland JN, Rahman T, Landry JL, Callens JE, Pandey G, Lam T, Kanyo J, Nairn AC, Dracheva S, Hurd YL. Ellis RJ, et al. Among authors: callens je. Biol Psychiatry. 2024 Dec 24:S0006-3223(24)01815-8. doi: 10.1016/j.biopsych.2024.12.007. Online ahead of print. Biol Psychiatry. 2024. PMID: 39725299
Severe udder cleft dermatitis lesion transcriptomics points to an impaired skin barrier, defective wound repair and a dysregulated inflammatory response as key elements in the pathogenesis.
Vermeersch AS, Ali M, Gansemans Y, Van Nieuwerburgh F, Geldhof P, Ducatelle R, Deforce D, Callens J, Opsomer G. Vermeersch AS, et al. Among authors: callens j. PLoS One. 2023 Jul 24;18(7):e0288347. doi: 10.1371/journal.pone.0288347. eCollection 2023. PLoS One. 2023. PMID: 37486897 Free PMC article.
Mirikizumab as Induction and Maintenance Therapy for Ulcerative Colitis.
D'Haens G, Dubinsky M, Kobayashi T, Irving PM, Howaldt S, Pokrotnieks J, Krueger K, Laskowski J, Li X, Lissoos T, Milata J, Morris N, Arora V, Milch C, Sandborn W, Sands BE; LUCENT Study Group. D'Haens G, et al. N Engl J Med. 2023 Jun 29;388(26):2444-2455. doi: 10.1056/NEJMoa2207940. N Engl J Med. 2023. PMID: 37379135 Clinical Trial.
81 results