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Novel substituted (Z)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-one and (Z)-(+/-)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol derivatives as potent thermal sensitizing agents.
Sonar VN, Thirupathi Reddy Y, Sekhar KR, Sasi S, Freeman ML, Crooks PA. Sonar VN, et al. Among authors: freeman ml. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6821-4. doi: 10.1016/j.bmcl.2007.10.035. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17980582 Free PMC article.
Novel substituted (Z)-5-((N-benzyl-1H-indol-3-yl)methylene)imidazolidine-2,4-diones and 5-((N-benzyl-1H-indol-3-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-triones as potent radio-sensitizing agents.
Reddy YT, Sekhar KR, Sasi N, Reddy PN, Freeman ML, Crooks PA. Reddy YT, et al. Among authors: freeman ml. Bioorg Med Chem Lett. 2010 Jan 15;20(2):600-2. doi: 10.1016/j.bmcl.2009.11.082. Epub 2009 Nov 22. Bioorg Med Chem Lett. 2010. PMID: 20005706 Free PMC article.
Targeting nucleophosmin 1 represents a rational strategy for radiation sensitization.
Sekhar KR, Benamar M, Venkateswaran A, Sasi S, Penthala NR, Crooks PA, Hann SR, Geng L, Balusu R, Abbas T, Freeman ML. Sekhar KR, et al. Among authors: freeman ml. Int J Radiat Oncol Biol Phys. 2014 Aug 1;89(5):1106-1114. doi: 10.1016/j.ijrobp.2014.04.012. Epub 2014 Jul 8. Int J Radiat Oncol Biol Phys. 2014. PMID: 25035215 Free PMC article.
486 results