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Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.
Gardenghi S, Marongiu MF, Ramos P, Guy E, Breda L, Chadburn A, Liu Y, Amariglio N, Rechavi G, Rachmilewitz EA, Breuer W, Cabantchik ZI, Wrighting DM, Andrews NC, de Sousa M, Giardina PJ, Grady RW, Rivella S. Gardenghi S, et al. Among authors: rivella s. Blood. 2007 Jun 1;109(11):5027-35. doi: 10.1182/blood-2006-09-048868. Epub 2007 Feb 13. Blood. 2007. PMID: 17299088 Free PMC article.
Decreased hepcidin mRNA expression in thalassemic mice.
Adamsky K, Weizer O, Amariglio N, Breda L, Harmelin A, Rivella S, Rachmilewitz E, Rechavi G. Adamsky K, et al. Among authors: rivella s. Br J Haematol. 2004 Jan;124(1):123-4. doi: 10.1046/j.1365-2141.2003.04734.x. Br J Haematol. 2004. PMID: 14675418 Free article. No abstract available.
Protective role of calreticulin in HFE hemochromatosis.
Pinto JP, Ramos P, de Almeida SF, Oliveira S, Breda L, Michalak M, Porto G, Rivella S, de Sousa M. Pinto JP, et al. Among authors: rivella s. Free Radic Biol Med. 2008 Jan 1;44(1):99-108. doi: 10.1016/j.freeradbiomed.2007.09.014. Epub 2007 Oct 4. Free Radic Biol Med. 2008. PMID: 18045552
159 results