Ivanov AA - Search Results

1

Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate.

Ivanov AA, Ko H, Cosyn L, Maddileti S, Besada P, Fricks I, Costanzi S, Harden TK, Calenbergh SV, Jacobson KA. Ivanov AA, et al. J Med Chem. 2007 Mar 22;50(6):1166-76. doi: 10.1021/jm060903o. Epub 2007 Feb 16. J Med Chem. 2007. PMID: 17302398 Free PMC article.

2

Structure-activity relationships of 2,N(6),5'-substituted adenosine derivatives with potent activity at the A2B adenosine receptor.

Adachi H, Palaniappan KK, Ivanov AA, Bergman N, Gao ZG, Jacobson KA. Adachi H, et al. Among authors: ivanov aa. J Med Chem. 2007 Apr 19;50(8):1810-27. doi: 10.1021/jm061278q. Epub 2007 Mar 23. J Med Chem. 2007. PMID: 17378544 Free PMC article.

3

Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor.

Ko H, Fricks I, Ivanov AA, Harden TK, Jacobson KA. Ko H, et al. Among authors: ivanov aa. J Med Chem. 2007 May 3;50(9):2030-9. doi: 10.1021/jm061222w. Epub 2007 Apr 4. J Med Chem. 2007. PMID: 17407275 Free PMC article.

4

Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists.

Ivanov AA, Wang B, Klutz AM, Chen VL, Gao ZG, Jacobson KA. Ivanov AA, et al. J Med Chem. 2008 Apr 10;51(7):2088-99. doi: 10.1021/jm701442d. Epub 2008 Mar 6. J Med Chem. 2008. PMID: 18321038 Free PMC article.

5

Molecular modeling of a PAMAM-CGS21680 dendrimer bound to an A2A adenosine receptor homodimer.

Ivanov AA, Jacobson KA. Ivanov AA, et al. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4312-5. doi: 10.1016/j.bmcl.2008.06.087. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18639453 Free PMC article.

6

Evaluation of homology modeling of G-protein-coupled receptors in light of the A(2A) adenosine receptor crystallographic structure.

Ivanov AA, Barak D, Jacobson KA. Ivanov AA, et al. J Med Chem. 2009 May 28;52(10):3284-92. doi: 10.1021/jm801533x. J Med Chem. 2009. PMID: 19402631 Free PMC article.

7

Functionalized congeners of A3 adenosine receptor-selective nucleosides containing a bicyclo[3.1.0]hexane ring system.

Tosh DK, Chinn M, Ivanov AA, Klutz AM, Gao ZG, Jacobson KA. Tosh DK, et al. Among authors: ivanov aa. J Med Chem. 2009 Dec 10;52(23):7580-92. doi: 10.1021/jm900426g. J Med Chem. 2009. PMID: 19499950 Free PMC article.

8

Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucose.

Ko H, Das A, Carter RL, Fricks IP, Zhou Y, Ivanov AA, Melman A, Joshi BV, Kovác P, Hajduch J, Kirk KL, Harden TK, Jacobson KA. Ko H, et al. Among authors: ivanov aa. Bioorg Med Chem. 2009 Jul 15;17(14):5298-311. doi: 10.1016/j.bmc.2009.05.024. Epub 2009 May 15. Bioorg Med Chem. 2009. PMID: 19502066 Free PMC article.

9

Enhanced potency of nucleotide-dendrimer conjugates as agonists of the P2Y14 receptor: multivalent effect in G protein-coupled receptor recognition.

Das A, Zhou Y, Ivanov AA, Carter RL, Harden TK, Jacobson KA. Das A, et al. Among authors: ivanov aa. Bioconjug Chem. 2009 Aug 19;20(8):1650-9. doi: 10.1021/bc900206g. Epub 2009 Jul 2. Bioconjug Chem. 2009. PMID: 19572637 Free PMC article.

10

Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors.

Jacobson KA, Costanzi S, Ivanov AA, Tchilibon S, Besada P, Gao ZG, Maddileti S, Harden TK. Jacobson KA, et al. Among authors: ivanov aa. Biochem Pharmacol. 2006 Feb 14;71(4):540-9. doi: 10.1016/j.bcp.2005.11.010. Epub 2005 Dec 15. Biochem Pharmacol. 2006. PMID: 16359641 Free PMC article.

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