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Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice.
Nelson RL, Guo Z, Halagappa VM, Pearson M, Gray AJ, Matsuoka Y, Brown M, Martin B, Iyun T, Maudsley S, Clark RF, Mattson MP. Nelson RL, et al. Among authors: pearson m. Exp Neurol. 2007 May;205(1):166-76. doi: 10.1016/j.expneurol.2007.01.037. Epub 2007 Feb 13. Exp Neurol. 2007. PMID: 17368447 Free PMC article.
Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma.
Johnson JB, Summer W, Cutler RG, Martin B, Hyun DH, Dixit VD, Pearson M, Nassar M, Telljohann R, Maudsley S, Carlson O, John S, Laub DR, Mattson MP. Johnson JB, et al. Among authors: pearson m. Free Radic Biol Med. 2007 Mar 1;42(5):665-74. doi: 10.1016/j.freeradbiomed.2006.12.005. Epub 2006 Dec 14. Free Radic Biol Med. 2007. PMID: 17291990 Free PMC article. Clinical Trial.
Antenatal pelvic floor muscle exercise intervention led by midwives in England to reduce postnatal urinary incontinence: APPEAL feasibility and pilot randomised controlled cluster trial.
MacArthur C, Bick D, Salmon V, Jones E, Hay-Smith J, Bishop J, Gkini E, Hemming K, Webb S, Pearson M, Coleman T, Terry R, Edwards E, Frawley H, Oborn E, Dean S. MacArthur C, et al. Among authors: pearson m. BMJ Open. 2025 Jan 20;15(1):e091248. doi: 10.1136/bmjopen-2024-091248. BMJ Open. 2025. PMID: 39832969 Free PMC article. Clinical Trial.
Pan-KRAS inhibitors BI-2493 and BI-2865 display potent anti-tumor activity in tumors with KRAS wild-type allele amplification.
Tedeschi A, Schischlik F, Rocchetti F, Popow J, Ebner F, Gerlach D, Geyer A, Santoro V, Boghossian AS, Rees MG, Ronan MM, Roth JA, Lipp J, Samwer M, Gmachl M, Kraut N, Pearson M, Rudolph D. Tedeschi A, et al. Among authors: pearson m. Mol Cancer Ther. 2024 Dec 23. doi: 10.1158/1535-7163.MCT-24-0386. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39711431
Understanding European patterns of deprescribing antithrombotic medication during end-of-life care in patients with cancer.
Martens ESL, Becker D, Abele C, Abbel D, Achterberg WP, Bax JJ, Bertoletti L, Edwards ME, Font C, Gava A, Goedegebuur J, Højen AA, Huisman MV, Kruip MJHA, Mahé I, Mooijaart SP, Pearson M, Seddon K, Szmit S, Noble SIR, Klok FA, Konstantinides SV. Martens ESL, et al. Among authors: pearson m. Thromb Res. 2025 Jan;245:109205. doi: 10.1016/j.thromres.2024.109205. Epub 2024 Nov 9. Thromb Res. 2025. PMID: 39667100 Free article.
A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer.
Jung P, Glaser SP, Han J, Popa A, Pisarsky L, Feng N, Geyer A, Haderk F, Alpar D, Bristow C, Schmittner S, Traexler PE, Mahendra M, Poehn B, Gandhi P, Fiorelli R, Awate S, Budano N, Martin F, Albrecht C, Drobits-Handl B, Anand SS, Kasturirangan S, Trapani F, Schweifer N, Marszalek JR, Tontsch-Grunt U, Pearson M, Heffernan TP, Kraut N, Vellano CP, García-Martínez JM. Jung P, et al. Among authors: pearson m. MAbs. 2024 Jan-Dec;16(1):2438173. doi: 10.1080/19420862.2024.2438173. Epub 2024 Dec 9. MAbs. 2024. PMID: 39654063 Free PMC article.
1,567 results