Howell SB - Search Results

1

Phase I and pharmacokinetic trial of AP5346, a DACH-platinum-polymer conjugate, administered weekly for three out of every 4 weeks to advanced solid tumor patients.

Campone M, Rademaker-Lakhai JM, Bennouna J, Howell SB, Nowotnik DP, Beijnen JH, Schellens JH. Campone M, et al. Among authors: howell sb. Cancer Chemother Pharmacol. 2007 Sep;60(4):523-33. doi: 10.1007/s00280-006-0397-0. Epub 2007 Feb 17. Cancer Chemother Pharmacol. 2007. PMID: 17308894 Clinical Trial.

2

A Phase I and pharmacological study of the platinum polymer AP5280 given as an intravenous infusion once every 3 weeks in patients with solid tumors.

Rademaker-Lakhai JM, Terret C, Howell SB, Baud CM, De Boer RF, Pluim D, Beijnen JH, Schellens JH, Droz JP. Rademaker-Lakhai JM, et al. Among authors: howell sb. Clin Cancer Res. 2004 May 15;10(10):3386-95. doi: 10.1158/1078-0432.CCR-03-0315. Clin Cancer Res. 2004. PMID: 15161693 Clinical Trial.

3

Preclinical efficacy and pharmacokinetics of AP5346, a novel diaminocyclohexane-platinum tumor-targeting drug delivery system.

Rice JR, Gerberich JL, Nowotnik DP, Howell SB. Rice JR, et al. Among authors: howell sb. Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2248-54. doi: 10.1158/1078-0432.CCR-05-2169. Clin Cancer Res. 2006. PMID: 16609041

4

Improved targeting of platinum chemotherapeutics. the antitumour activity of the HPMA copolymer platinum agent AP5280 in murine tumour models.

Lin X, Zhang Q, Rice JR, Stewart DR, Nowotnik DP, Howell SB. Lin X, et al. Among authors: howell sb. Eur J Cancer. 2004 Jan;40(2):291-7. doi: 10.1016/j.ejca.2003.09.022. Eur J Cancer. 2004. PMID: 14728945

5

A phase I and pharmacokinetic study of high dose tamoxifen and weekly cisplatin in patients with metastatic melanoma.

McClay EF, McClay ME, Jones JA, Winski PJ, Christen RD, Howell SB, Hall PD. McClay EF, et al. Among authors: howell sb. Cancer. 1997 Mar 1;79(5):1037-43. doi: 10.1002/(sici)1097-0142(19970301)79:5<1037::aid-cncr22>3.0.co;2-1. Cancer. 1997. PMID: 9041168 Clinical Trial.

6

A phase II/pharmacokinetic trial of high-dose progesterone in combination with paclitaxel.

Aebi S, Schnider TW, Los G, Heath DD, Darrah D, Kirmani S, McClay EF, D'Agostino H, Plaxe SC, Fink D, De las Alas MM, Howell SB, Christen RD. Aebi S, et al. Among authors: howell sb. Cancer Chemother Pharmacol. 1999;44(3):259-65. doi: 10.1007/s002800050976. Cancer Chemother Pharmacol. 1999. PMID: 10453729 Clinical Trial.

7

Selective intra-arterial infusion of high-dose cisplatin in patients with advanced head and neck cancer results in high tumor platinum concentrations and cisplatin-DNA adduct formation.

Los G, Blommaert fA, Barton R, Heath DD, den Engelse L, Hanchett C, Vicario D, Weisman R, Robbins KT, Howell SB. Los G, et al. Among authors: howell sb. Cancer Chemother Pharmacol. 1995;37(1-2):150-4. doi: 10.1007/BF00685642. Cancer Chemother Pharmacol. 1995. PMID: 7497585

8

Modulation of the cellular pharmacology of JM118, the major metabolite of satraplatin, by copper influx and efflux transporters.

Samimi G, Howell SB. Samimi G, et al. Among authors: howell sb. Cancer Chemother Pharmacol. 2006 Jun;57(6):781-8. doi: 10.1007/s00280-005-0121-5. Epub 2005 Sep 17. Cancer Chemother Pharmacol. 2006. PMID: 16170571

9

Phase I trial of combination therapy of cancer with N-phosphonacetyl-L-aspartic acid and dipyridamole.

Markman M, Chan TC, Cleary S, Howell SB. Markman M, et al. Among authors: howell sb. Cancer Chemother Pharmacol. 1987;19(1):80-3. doi: 10.1007/BF00296262. Cancer Chemother Pharmacol. 1987. PMID: 3815730

10

cDNA microarray-based identification of genes and pathways associated with oxaliplatin resistance.

Samimi G, Manorek G, Castel R, Breaux JK, Cheng TC, Berry CC, Los G, Howell SB. Samimi G, et al. Among authors: howell sb. Cancer Chemother Pharmacol. 2005 Jan;55(1):1-11. doi: 10.1007/s00280-004-0819-9. Epub 2004 Sep 16. Cancer Chemother Pharmacol. 2005. PMID: 15378272

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