Vainchenker W - Search Results

1

The myeloproliferative disorder-associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3.

Hookham MB, Elliott J, Suessmuth Y, Staerk J, Ward AC, Vainchenker W, Percy MJ, McMullin MF, Constantinescu SN, Johnston JA. Hookham MB, et al. Among authors: vainchenker w. Blood. 2007 Jun 1;109(11):4924-9. doi: 10.1182/blood-2006-08-039735. Epub 2007 Feb 22. Blood. 2007. PMID: 17317861 Free article.

2

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera.

James C, Ugo V, Le Couédic JP, Staerk J, Delhommeau F, Lacout C, Garçon L, Raslova H, Berger R, Bennaceur-Griscelli A, Villeval JL, Constantinescu SN, Casadevall N, Vainchenker W. James C, et al. Among authors: vainchenker w. Nature. 2005 Apr 28;434(7037):1144-8. doi: 10.1038/nature03546. Nature. 2005. PMID: 15793561

3

Role of tyrosine kinases and phosphatases in polycythemia vera.

Zhao ZJ, Vainchenker W, Krantz SB, Casadevall N, Constantinescu SN. Zhao ZJ, et al. Among authors: vainchenker w. Semin Hematol. 2005 Oct;42(4):221-9. doi: 10.1053/j.seminhematol.2005.05.019. Semin Hematol. 2005. PMID: 16210035 Review.

4

JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.

Staerk J, Kallin A, Demoulin JB, Vainchenker W, Constantinescu SN. Staerk J, et al. Among authors: vainchenker w. J Biol Chem. 2005 Dec 23;280(51):41893-9. doi: 10.1074/jbc.C500358200. Epub 2005 Oct 19. J Biol Chem. 2005. PMID: 16239216 Free article.

5

An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor.

Staerk J, Lacout C, Sato T, Smith SO, Vainchenker W, Constantinescu SN. Staerk J, et al. Among authors: vainchenker w. Blood. 2006 Mar 1;107(5):1864-71. doi: 10.1182/blood-2005-06-2600. Epub 2005 Oct 25. Blood. 2006. PMID: 16249382 Free PMC article.

6

A JAK2 mutation in myeloproliferative disorders: pathogenesis and therapeutic and scientific prospects.

James C, Ugo V, Casadevall N, Constantinescu SN, Vainchenker W. James C, et al. Among authors: vainchenker w. Trends Mol Med. 2005 Dec;11(12):546-54. doi: 10.1016/j.molmed.2005.10.003. Epub 2005 Nov 3. Trends Mol Med. 2005. PMID: 16271512 Review.

7

A unique activating mutation in JAK2 (V617F) is at the origin of polycythemia vera and allows a new classification of myeloproliferative diseases.

Vainchenker W, Constantinescu SN. Vainchenker W, et al. Hematology Am Soc Hematol Educ Program. 2005:195-200. doi: 10.1182/asheducation-2005.1.195. Hematology Am Soc Hematol Educ Program. 2005. PMID: 16304380

8

Genetic and clinical implications of the Val617Phe JAK2 mutation in 72 families with myeloproliferative disorders.

Bellanné-Chantelot C, Chaumarel I, Labopin M, Bellanger F, Barbu V, De Toma C, Delhommeau F, Casadevall N, Vainchenker W, Thomas G, Najman A. Bellanné-Chantelot C, et al. Among authors: vainchenker w. Blood. 2006 Jul 1;108(1):346-52. doi: 10.1182/blood-2005-12-4852. Epub 2006 Mar 14. Blood. 2006. PMID: 16537803 Free article.

9

JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis.

Lacout C, Pisani DF, Tulliez M, Gachelin FM, Vainchenker W, Villeval JL. Lacout C, et al. Among authors: vainchenker w. Blood. 2006 Sep 1;108(5):1652-60. doi: 10.1182/blood-2006-02-002030. Epub 2006 May 2. Blood. 2006. PMID: 16670266 Free article.

10

JAK2, the JAK2 V617F mutant and cytokine receptors.

Staerk J, Kallin A, Royer Y, Diaconu CC, Dusa A, Demoulin JB, Vainchenker W, Constantinescu SN. Staerk J, et al. Among authors: vainchenker w. Pathol Biol (Paris). 2007 Mar;55(2):88-91. doi: 10.1016/j.patbio.2006.06.003. Epub 2006 Aug 14. Pathol Biol (Paris). 2007. PMID: 16904848 Review.

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