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Specificity of pyridinium inhibitors of the ubiquinone reduction sites in mitochondrial complex I.
Miyoshi H, Iwata J, Sakamoto K, Furukawa H, Takada M, Iwamura H, Watanabe T, Kodama Y. Miyoshi H, et al. J Biol Chem. 1998 Jul 10;273(28):17368-74. doi: 10.1074/jbc.273.28.17368. J Biol Chem. 1998. PMID: 9651320 Free article.
The marked biphasic nature of the dose-response curve for inhibition of the enzyme by MP-6(N-methyl-4-[2-(p-tert-butylbenzyl)propyl]pyridinium) makes this compound the first selective inhibitor of the two sites (Miyoshi, H., Inoue, M., Okamoto, S., Ohshima, M., Saka …
The marked biphasic nature of the dose-response curve for inhibition of the enzyme by MP-6(N-methyl-4-[2-(p-tert-butylbenzyl)propyl]pyridini …
Isolation and characterizations of quinone analogue-resistant mutants of bo-type ubiquinol oxidase from Escherichia coli.
Sato-Watanabe M, Mogi T, Sakamoto K, Miyoshi H, Anraku Y. Sato-Watanabe M, et al. Among authors: miyoshi h. Biochemistry. 1998 Sep 15;37(37):12744-52. doi: 10.1021/bi981184l. Biochemistry. 1998. PMID: 9737851
To probe the location and structural properties of the ubiquinol oxidation site, we isolated and characterized five or 10 spontaneous mutants resistant to either 2,6-dimethyl-1,4-benzoquinone, 2,6-dichloro-4-nitrophenol, or 2,6-dichloro-4-dicyanovinylphenol, the potent competitiv …
To probe the location and structural properties of the ubiquinol oxidation site, we isolated and characterized five or 10 spontaneous mutant …
1,347 results