Specificity of pyridinium inhibitors of the ubiquinone reduction sites in mitochondrial complex I.
Miyoshi H, Iwata J, Sakamoto K, Furukawa H, Takada M, Iwamura H, Watanabe T, Kodama Y.
Miyoshi H, et al.
J Biol Chem. 1998 Jul 10;273(28):17368-74. doi: 10.1074/jbc.273.28.17368.
J Biol Chem. 1998.
PMID: 9651320
Free article.
The marked biphasic nature of the dose-response curve for inhibition of the enzyme by MP-6(N-methyl-4-[2-(p-tert-butylbenzyl)propyl]pyridinium) makes this compound the first selective inhibitor of the two sites (Miyoshi, H., Inoue, M., Okamoto, S., Ohshima, M., Saka …
The marked biphasic nature of the dose-response curve for inhibition of the enzyme by MP-6(N-methyl-4-[2-(p-tert-butylbenzyl)propyl]pyridini …