Tarling CA - Search Results

1

Structural and mechanistic analyses of endo-glycoceramidase II, a membrane-associated family 5 glycosidase in the Apo and GM3 ganglioside-bound forms.

Caines ME, Vaughan MD, Tarling CA, Hancock SM, Warren RA, Withers SG, Strynadka NC. Caines ME, et al. Among authors: tarling ca. J Biol Chem. 2007 May 11;282(19):14300-8. doi: 10.1074/jbc.M611455200. Epub 2007 Feb 28. J Biol Chem. 2007. PMID: 17329247 Free article.

2

Structural, thermodynamic, and kinetic analyses of tetrahydrooxazine-derived inhibitors bound to beta-glucosidases.

Gloster TM, Macdonald JM, Tarling CA, Stick RV, Withers SG, Davies GJ. Gloster TM, et al. Among authors: tarling ca. J Biol Chem. 2004 Nov 19;279(47):49236-42. doi: 10.1074/jbc.M407195200. Epub 2004 Sep 8. J Biol Chem. 2004. PMID: 15356002 Free article.

3

High-throughput screening of cell lysates for ganglioside synthesis.

Hancock SM, Tarling CA, Withers SG. Hancock SM, et al. Among authors: tarling ca. Anal Biochem. 2008 Nov 1;382(1):48-54. doi: 10.1016/j.ab.2008.07.023. Epub 2008 Jul 29. Anal Biochem. 2008. PMID: 18703011

4

Identification of the catalytic nucleophile of the family 29 alpha-L-fucosidase from Thermotoga maritima through trapping of a covalent glycosyl-enzyme intermediate and mutagenesis.

Tarling CA, He S, Sulzenbacher G, Bignon C, Bourne Y, Henrissat B, Withers SG. Tarling CA, et al. J Biol Chem. 2003 Nov 28;278(48):47394-9. doi: 10.1074/jbc.M306610200. Epub 2003 Sep 15. J Biol Chem. 2003. PMID: 12975375 Free article.

5

The donor subsite of trehalose-6-phosphate synthase: binary complexes with UDP-glucose and UDP-2-deoxy-2-fluoro-glucose at 2 A resolution.

Gibson RP, Tarling CA, Roberts S, Withers SG, Davies GJ. Gibson RP, et al. Among authors: tarling ca. J Biol Chem. 2004 Jan 16;279(3):1950-5. doi: 10.1074/jbc.M307643200. Epub 2003 Oct 21. J Biol Chem. 2004. PMID: 14570926 Free article.

6

Crystal structure of Thermotoga maritima alpha-L-fucosidase. Insights into the catalytic mechanism and the molecular basis for fucosidosis.

Sulzenbacher G, Bignon C, Nishimura T, Tarling CA, Withers SG, Henrissat B, Bourne Y. Sulzenbacher G, et al. Among authors: tarling ca. J Biol Chem. 2004 Mar 26;279(13):13119-28. doi: 10.1074/jbc.M313783200. Epub 2004 Jan 8. J Biol Chem. 2004. PMID: 14715651 Free article.

7

The synthesis of a series of modified mannotrisaccharides as probes of the enzymes involved in the early stages of mammalian complex N-glycan formation.

Tarling CA, Withers SG. Tarling CA, et al. Carbohydr Res. 2004 Oct 20;339(15):2487-97. doi: 10.1016/j.carres.2004.08.007. Carbohydr Res. 2004. PMID: 15476709

8

The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.

Caines ME, Hancock SM, Tarling CA, Wrodnigg TM, Stick RV, Stütz AE, Vasella A, Withers SG, Strynadka NC. Caines ME, et al. Among authors: tarling ca. Angew Chem Int Ed Engl. 2007;46(24):4474-6. doi: 10.1002/anie.200700268. Angew Chem Int Ed Engl. 2007. PMID: 17487923 No abstract available.

9

Recruitment of both uniform and differential binding energy in enzymatic catalysis: xylanases from families 10 and 11.

Wicki J, Schloegl J, Tarling CA, Withers SG. Wicki J, et al. Among authors: tarling ca. Biochemistry. 2007 Jun 12;46(23):6996-7005. doi: 10.1021/bi700359e. Epub 2007 May 16. Biochemistry. 2007. PMID: 17503782

10

Probing electrostatic interactions along the reaction pathway of a glycoside hydrolase: histidine characterization by NMR spectroscopy.

Schubert M, Poon DK, Wicki J, Tarling CA, Kwan EM, Nielsen JE, Withers SG, McIntosh LP. Schubert M, et al. Among authors: tarling ca. Biochemistry. 2007 Jun 26;46(25):7383-95. doi: 10.1021/bi700249m. Epub 2007 Jun 5. Biochemistry. 2007. PMID: 17547373

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