Gustafsson LL - Search Results

1

CYP3A5 genotype has an impact on the metabolism of the HIV protease inhibitor saquinavir.

Josephson F, Allqvist A, Janabi M, Sayi J, Aklillu E, Jande M, Mahindi M, Burhenne J, Bottiger Y, Gustafsson LL, Haefeli WE, Bertilsson L. Josephson F, et al. Among authors: gustafsson ll. Clin Pharmacol Ther. 2007 May;81(5):708-12. doi: 10.1038/sj.clpt.6100117. Epub 2007 Feb 28. Clin Pharmacol Ther. 2007. PMID: 17329995

2

The concentration-effect relationship of quinine-induced hearing impairment.

Paintaud G, Alván G, Berninger E, Gustafsson LL, Idrizbegovic E, Karlsson KK, Wakelkamp M. Paintaud G, et al. Among authors: gustafsson ll. Clin Pharmacol Ther. 1994 Mar;55(3):317-23. doi: 10.1038/clpt.1994.32. Clin Pharmacol Ther. 1994. PMID: 8143397

3

Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype.

Herrlin K, Massele AY, Jande M, Alm C, Tybring G, Abdi YA, Wennerholm A, Johansson I, Dahl ML, Bertilsson L, Gustafsson LL. Herrlin K, et al. Among authors: gustafsson ll. Clin Pharmacol Ther. 1998 Oct;64(4):391-401. doi: 10.1016/S0009-9236(98)90070-4. Clin Pharmacol Ther. 1998. PMID: 9797796

4

Metabolism of ropivacaine in humans is mediated by CYP1A2 and to a minor extent by CYP3A4: an interaction study with fluvoxamine and ketoconazole as in vivo inhibitors.

Arlander E, Ekström G, Alm C, Carrillo JA, Bielenstein M, Böttiger Y, Bertilsson L, Gustafsson LL. Arlander E, et al. Among authors: gustafsson ll. Clin Pharmacol Ther. 1998 Nov;64(5):484-91. doi: 10.1016/S0009-9236(98)90131-X. Clin Pharmacol Ther. 1998. PMID: 9834040 Clinical Trial.

5

The roles of cytochrome P450 3A4 and 1A2 in the 3-hydroxylation of quinine in vivo.

Mirghani RA, Hellgren U, Westerberg PA, Ericsson O, Bertilsson L, Gustafsson LL. Mirghani RA, et al. Among authors: gustafsson ll. Clin Pharmacol Ther. 1999 Nov;66(5):454-60. doi: 10.1016/S0009-9236(99)70008-1. Clin Pharmacol Ther. 1999. PMID: 10579472 Clinical Trial.

6

Ketoconazole inhibits the metabolism of tolterodine in subjects with deficient CYP2D6 activity.

Brynne N, Forslund C, Hallén B, Gustafsson LL, Bertilsson L. Brynne N, et al. Among authors: gustafsson ll. Br J Clin Pharmacol. 1999 Oct;48(4):564-72. doi: 10.1046/j.1365-2125.1999.00053.x. Br J Clin Pharmacol. 1999. PMID: 10583027 Free PMC article. Clinical Trial.

7

Decreased capacity for debrisoquine metabolism among black Tanzanians: analyses of the CYP2D6 genotype and phenotype.

Wennerholm A, Johansson I, Massele AY, Lande M, Alm C, Aden-Abdi Y, Dahl ML, Ingelman-Sundberg M, Bertilsson L, Gustafsson LL. Wennerholm A, et al. Among authors: gustafsson ll. Pharmacogenetics. 1999 Dec;9(6):707-14. Pharmacogenetics. 1999. PMID: 10634133

8

Slow chloroguanide metabolism in Tanzanians compared with white subjects and Asian subjects confirms a decreased CYP2C19 activity in relation to genotype.

Herrlin K, Massele AY, Rimoy G, Alm C, Rais M, Ericsson O, Bertilsson L, Gustafsson LL. Herrlin K, et al. Among authors: gustafsson ll. Clin Pharmacol Ther. 2000 Aug;68(2):189-98. doi: 10.1067/mcp.2000.108583. Clin Pharmacol Ther. 2000. PMID: 10976550 Clinical Trial.

9

Characterization of the CYP2D6*29 allele commonly present in a black Tanzanian population causing reduced catalytic activity.

Wennerholm A, Johansson I, Hidestrand M, Bertilsson L, Gustafsson LL, Ingelman-Sundberg M. Wennerholm A, et al. Among authors: gustafsson ll. Pharmacogenetics. 2001 Jul;11(5):417-27. doi: 10.1097/00008571-200107000-00005. Pharmacogenetics. 2001. PMID: 11470994

10

The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity.

Wennerholm A, Dandara C, Sayi J, Svensson JO, Abdi YA, Ingelman-Sundberg M, Bertilsson L, Hasler J, Gustafsson LL. Wennerholm A, et al. Among authors: gustafsson ll. Clin Pharmacol Ther. 2002 Jan;71(1):77-88. doi: 10.1067/mcp.2002.120239. Clin Pharmacol Ther. 2002. PMID: 11823760 Clinical Trial.

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