Bartus RT - Search Results

1

Neurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease.

Ramaswamy S, McBride JL, Herzog CD, Brandon E, Gasmi M, Bartus RT, Kordower JH. Ramaswamy S, et al. Among authors: bartus rt. Neurobiol Dis. 2007 May;26(2):375-84. doi: 10.1016/j.nbd.2007.01.003. Epub 2007 Jan 25. Neurobiol Dis. 2007. PMID: 17336076

2

AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: long-term efficacy and tolerability of CERE-120 for Parkinson's disease.

Gasmi M, Brandon EP, Herzog CD, Wilson A, Bishop KM, Hofer EK, Cunningham JJ, Printz MA, Kordower JH, Bartus RT. Gasmi M, et al. Among authors: bartus rt. Neurobiol Dis. 2007 Jul;27(1):67-76. doi: 10.1016/j.nbd.2007.04.003. Epub 2007 Apr 19. Neurobiol Dis. 2007. PMID: 17532642

3

Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease.

Ramaswamy S, McBride JL, Han I, Berry-Kravis EM, Zhou L, Herzog CD, Gasmi M, Bartus RT, Kordower JH. Ramaswamy S, et al. Among authors: bartus rt. Neurobiol Dis. 2009 Apr;34(1):40-50. doi: 10.1016/j.nbd.2008.12.005. Epub 2008 Dec 25. Neurobiol Dis. 2009. PMID: 19150499

4

Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease.

McBride JL, Ramaswamy S, Gasmi M, Bartus RT, Herzog CD, Brandon EP, Zhou L, Pitzer MR, Berry-Kravis EM, Kordower JH. McBride JL, et al. Among authors: bartus rt. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9345-50. doi: 10.1073/pnas.0508875103. Epub 2006 Jun 2. Proc Natl Acad Sci U S A. 2006. PMID: 16751280 Free PMC article.

5

Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys.

Kordower JH, Herzog CD, Dass B, Bakay RA, Stansell J 3rd, Gasmi M, Bartus RT. Kordower JH, et al. Among authors: bartus rt. Ann Neurol. 2006 Dec;60(6):706-15. doi: 10.1002/ana.21032. Ann Neurol. 2006. PMID: 17192932

6

Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies.

Bartus RT, Kordower JH, Johnson EM Jr, Brown L, Kruegel BR, Chu Y, Baumann TL, Lang AE, Olanow CW, Herzog CD. Bartus RT, et al. Neurobiol Dis. 2015 Jun;78:162-71. doi: 10.1016/j.nbd.2015.03.023. Epub 2015 Apr 2. Neurobiol Dis. 2015. PMID: 25841760

7

Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys.

Herzog CD, Dass B, Holden JE, Stansell J 3rd, Gasmi M, Tuszynski MH, Bartus RT, Kordower JH. Herzog CD, et al. Among authors: bartus rt. Mov Disord. 2007 Jun 15;22(8):1124-32. doi: 10.1002/mds.21503. Mov Disord. 2007. PMID: 17443702

8

Issues regarding gene therapy products for Parkinson's disease: the development of CERE-120 (AAV-NTN) as one reference point.

Bartus RT, Herzog CD, Bishop K, Ostrove JM, Tuszynski M, Kordower JH, Gasmi M. Bartus RT, et al. Parkinsonism Relat Disord. 2007;13 Suppl 3:S469-77. doi: 10.1016/S1353-8020(08)70052-X. Parkinsonism Relat Disord. 2007. PMID: 18267286 Review.

9

Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS.

Franz CK, Federici T, Yang J, Backus C, Oh SS, Teng Q, Carlton E, Bishop KM, Gasmi M, Bartus RT, Feldman EL, Boulis NM. Franz CK, et al. Among authors: bartus rt. Neurobiol Dis. 2009 Mar;33(3):473-81. doi: 10.1016/j.nbd.2008.12.003. Epub 2008 Dec 24. Neurobiol Dis. 2009. PMID: 19135533

10

Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease.

Herzog CD, Brown L, Gammon D, Kruegel B, Lin R, Wilson A, Bolton A, Printz M, Gasmi M, Bishop KM, Kordower JH, Bartus RT. Herzog CD, et al. Among authors: bartus rt. Neurosurgery. 2009 Apr;64(4):602-12; discussion 612-3. doi: 10.1227/01.NEU.0000340682.06068.01. Neurosurgery. 2009. PMID: 19349823

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