Vlahakis JZ - Search Results

1

Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: effect of halogen substitution in the phenyl ring.

Roman G, Riley JG, Vlahakis JZ, Kinobe RT, Brien JF, Nakatsu K, Szarek WA. Roman G, et al. Among authors: vlahakis jz. Bioorg Med Chem. 2007 May 1;15(9):3225-34. doi: 10.1016/j.bmc.2007.02.034. Epub 2007 Feb 22. Bioorg Med Chem. 2007. PMID: 17339115

2

Synthesis and evaluation of azalanstat analogues as heme oxygenase inhibitors.

Vlahakis JZ, Kinobe RT, Bowers RJ, Brien JF, Nakatsu K, Szarek WA. Vlahakis JZ, et al. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1457-61. doi: 10.1016/j.bmcl.2004.12.075. Bioorg Med Chem Lett. 2005. PMID: 15713406

3

Selectivity of imidazole-dioxolane compounds for in vitro inhibition of microsomal haem oxygenase isoforms.

Kinobe RT, Vlahakis JZ, Vreman HJ, Stevenson DK, Brien JF, Szarek WA, Nakatsu K. Kinobe RT, et al. Among authors: vlahakis jz. Br J Pharmacol. 2006 Feb;147(3):307-15. doi: 10.1038/sj.bjp.0706555. Br J Pharmacol. 2006. PMID: 16331285 Free PMC article.

4

Anti-Plasmodium activity of imidazole-dioxolane compounds.

Vlahakis JZ, Kinobe RT, Nakatsu K, Szarek WA, Crandall IE. Vlahakis JZ, et al. Bioorg Med Chem Lett. 2006 May 1;16(9):2396-406. doi: 10.1016/j.bmcl.2006.01.122. Epub 2006 Feb 21. Bioorg Med Chem Lett. 2006. PMID: 16495054

5

Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugs.

Kinobe RT, Dercho RA, Vlahakis JZ, Brien JF, Szarek WA, Nakatsu K. Kinobe RT, et al. Among authors: vlahakis jz. J Pharmacol Exp Ther. 2006 Oct;319(1):277-84. doi: 10.1124/jpet.106.102699. Epub 2006 Jun 28. J Pharmacol Exp Ther. 2006. PMID: 16807364

6

Imidazole-dioxolane compounds as isozyme-selective heme oxygenase inhibitors.

Vlahakis JZ, Kinobe RT, Bowers RJ, Brien JF, Nakatsu K, Szarek WA. Vlahakis JZ, et al. J Med Chem. 2006 Jul 13;49(14):4437-41. doi: 10.1021/jm0511435. J Med Chem. 2006. PMID: 16821802

7

Heme oxygenase activity in fetal and adult sheep is not altered by acclimatization to high altitude hypoxia.

Kinobe RT, Vlahakis JZ, Soong JM, Szarek WA, Brien JF, Longo LD, Nakatsu K. Kinobe RT, et al. Among authors: vlahakis jz. Can J Physiol Pharmacol. 2006 Aug-Sep;84(8-9):893-901. doi: 10.1139/y06-034. Can J Physiol Pharmacol. 2006. PMID: 17111034

8

Effectiveness of novel imidazole-dioxolane heme oxygenase inhibitors in renal proximal tubule epithelial cells.

Kinobe RT, Ji Y, Vlahakis JZ, Motterlini R, Brien JF, Szarek WA, Nakatsu K. Kinobe RT, et al. Among authors: vlahakis jz. J Pharmacol Exp Ther. 2007 Dec;323(3):763-70. doi: 10.1124/jpet.107.119800. Epub 2007 Aug 30. J Pharmacol Exp Ther. 2007. PMID: 17761847

9

Anti-Plasmodium activity of tetrazolium salts.

Cui X, Vlahakis JZ, Crandall IE, Szarek WA. Cui X, et al. Among authors: vlahakis jz. Bioorg Med Chem. 2008 Feb 15;16(4):1927-47. doi: 10.1016/j.bmc.2007.11.005. Epub 2007 Nov 5. Bioorg Med Chem. 2008. PMID: 18078758

10

X-ray crystal structure of human heme oxygenase-1 in complex with 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone: a common binding mode for imidazole-based heme oxygenase-1 inhibitors.

Rahman MN, Vlahakis JZ, Szarek WA, Nakatsu K, Jia Z. Rahman MN, et al. Among authors: vlahakis jz. J Med Chem. 2008 Oct 9;51(19):5943-52. doi: 10.1021/jm800505m. Epub 2008 Sep 18. J Med Chem. 2008. PMID: 18798608

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