O'Dwyer PJ - Search Results

1

Inhibition of G1/S transition potentiates oxaliplatin-induced cell death in colon cancer cell lines.

Rakitina TV, Vasilevskaya IA, O'Dwyer PJ. Rakitina TV, et al. Biochem Pharmacol. 2007 Jun 1;73(11):1715-26. doi: 10.1016/j.bcp.2007.01.037. Epub 2007 Feb 4. Biochem Pharmacol. 2007. PMID: 17343830

2

Disruption of signaling through SEK1 and MKK7 yields differential responses in hypoxic colon cancer cells treated with oxaliplatin.

Vasilevskaya IA, Selvakumaran M, O'Dwyer PJ. Vasilevskaya IA, et al. Mol Pharmacol. 2008 Jul;74(1):246-54. doi: 10.1124/mol.107.044644. Epub 2008 Apr 24. Mol Pharmacol. 2008. PMID: 18436711

3

Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy.

Selvakumaran M, Amaravadi RK, Vasilevskaya IA, O'Dwyer PJ. Selvakumaran M, et al. Clin Cancer Res. 2013 Jun 1;19(11):2995-3007. doi: 10.1158/1078-0432.CCR-12-1542. Epub 2013 Mar 5. Clin Cancer Res. 2013. PMID: 23461901

4

Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents.

Vasilevskaya IA, Selvakumaran M, Hierro LC, Goldstein SR, Winkler JD, O'Dwyer PJ. Vasilevskaya IA, et al. Clin Cancer Res. 2015 Sep 15;21(18):4143-52. doi: 10.1158/1078-0432.CCR-15-0352. Epub 2015 May 28. Clin Cancer Res. 2015. PMID: 26023085 Free PMC article.

5

Additive interaction of oxaliplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines results from inhibition of nuclear factor kappaB signaling.

Rakitina TV, Vasilevskaya IA, O'Dwyer PJ. Rakitina TV, et al. Cancer Res. 2003 Dec 15;63(24):8600-5. Cancer Res. 2003. PMID: 14695170

6

Quantitative effects on c-Jun N-terminal protein kinase signaling determine synergistic interaction of cisplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines.

Vasilevskaya IA, Rakitina TV, O'Dwyer PJ. Vasilevskaya IA, et al. Mol Pharmacol. 2004 Jan;65(1):235-43. doi: 10.1124/mol.65.1.235. Mol Pharmacol. 2004. PMID: 14722256

7

17-Allylamino-17-demethoxygeldanamycin overcomes TRAIL resistance in colon cancer cell lines.

Vasilevskaya IA, O'Dwyer PJ. Vasilevskaya IA, et al. Biochem Pharmacol. 2005 Aug 15;70(4):580-9. doi: 10.1016/j.bcp.2005.05.018. Biochem Pharmacol. 2005. PMID: 15993848

8

JNK1 Inhibition Attenuates Hypoxia-Induced Autophagy and Sensitizes to Chemotherapy.

Vasilevskaya IA, Selvakumaran M, Roberts D, O'Dwyer PJ. Vasilevskaya IA, et al. Mol Cancer Res. 2016 Aug;14(8):753-63. doi: 10.1158/1541-7786.MCR-16-0035. Epub 2016 May 23. Mol Cancer Res. 2016. PMID: 27216154 Free PMC article.

9

Geldanamycin and its 17-allylamino-17-demethoxy analogue antagonize the action of Cisplatin in human colon adenocarcinoma cells: differential caspase activation as a basis for interaction.

Vasilevskaya IA, Rakitina TV, O'Dwyer PJ. Vasilevskaya IA, et al. Cancer Res. 2003 Jun 15;63(12):3241-6. Cancer Res. 2003. PMID: 12810654

10

Role of Jun and Jun kinase in resistance of cancer cells to therapy.

Vasilevskaya I, O'Dwyer PJ. Vasilevskaya I, et al. Drug Resist Updat. 2003 Jun;6(3):147-56. doi: 10.1016/s1368-7646(03)00043-8. Drug Resist Updat. 2003. PMID: 12860462 Review.

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