Leslie NR - Search Results

1

Stimulation of PI 3-kinase signaling via inhibition of the tumor suppressor phosphatase, PTEN.

Downes CP, Ross S, Maccario H, Perera N, Davidson L, Leslie NR. Downes CP, et al. Among authors: leslie nr. Adv Enzyme Regul. 2007;47:184-94. doi: 10.1016/j.advenzreg.2006.12.018. Epub 2006 Dec 30. Adv Enzyme Regul. 2007. PMID: 17343901 Review. No abstract available.

2

Analysis of the cellular functions of PTEN using catalytic domain and C-terminal mutations: differential effects of C-terminal deletion on signalling pathways downstream of phosphoinositide 3-kinase.

Leslie NR, Gray A, Pass I, Orchiston EA, Downes CP. Leslie NR, et al. Biochem J. 2000 Mar 15;346 Pt 3(Pt 3):827-33. Biochem J. 2000. PMID: 10698713 Free PMC article.

3

Beta1-integrin and PTEN control the phosphorylation of protein kinase C.

Parekh DB, Katso RM, Leslie NR, Downes CP, Procyk KJ, Waterfield MD, Parker PJ. Parekh DB, et al. Among authors: leslie nr. Biochem J. 2000 Dec 1;352 Pt 2(Pt 2):425-33. Biochem J. 2000. PMID: 11085936 Free PMC article.

4

Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions.

Leslie NR, Bennett D, Gray A, Pass I, Hoang-Xuan K, Downes CP. Leslie NR, et al. Biochem J. 2001 Jul 15;357(Pt 2):427-35. doi: 10.1042/0264-6021:3570427. Biochem J. 2001. PMID: 11439092 Free PMC article.

5

Antagonism of PI 3-kinase-dependent signalling pathways by the tumour suppressor protein, PTEN.

Downes CP, Bennett D, McConnachie G, Leslie NR, Pass I, MacPhee C, Patel L, Gray A. Downes CP, et al. Among authors: leslie nr. Biochem Soc Trans. 2001 Nov;29(Pt 6):846-51. doi: 10.1042/0300-5127:0290846. Biochem Soc Trans. 2001. PMID: 11709086 Review.

6

TPIP: a novel phosphoinositide 3-phosphatase.

Walker SM, Downes CP, Leslie NR. Walker SM, et al. Among authors: leslie nr. Biochem J. 2001 Dec 1;360(Pt 2):277-83. doi: 10.1042/0264-6021:3600277. Biochem J. 2001. PMID: 11716755 Free PMC article.

7

PTEN: The down side of PI 3-kinase signalling.

Leslie NR, Downes CP. Leslie NR, et al. Cell Signal. 2002 Apr;14(4):285-95. doi: 10.1016/s0898-6568(01)00234-0. Cell Signal. 2002. PMID: 11858936 Review.

8

Redox regulation of PI 3-kinase signalling via inactivation of PTEN.

Leslie NR, Bennett D, Lindsay YE, Stewart H, Gray A, Downes CP. Leslie NR, et al. EMBO J. 2003 Oct 15;22(20):5501-10. doi: 10.1093/emboj/cdg513. EMBO J. 2003. PMID: 14532122 Free PMC article.

9

PTEN M-CBR3, a versatile and selective regulator of inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5). Evidence for Ins(1,3,4,5,6)P5 as a proliferative signal.

Orchiston EA, Bennett D, Leslie NR, Clarke RG, Winward L, Downes CP, Safrany ST. Orchiston EA, et al. Among authors: leslie nr. J Biol Chem. 2004 Jan 9;279(2):1116-22. doi: 10.1074/jbc.M310933200. Epub 2003 Oct 15. J Biol Chem. 2004. PMID: 14561749 Free article.

10

Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy.

Watt SA, Kimber WA, Fleming IN, Leslie NR, Downes CP, Lucocq JM. Watt SA, et al. Among authors: leslie nr. Biochem J. 2004 Feb 1;377(Pt 3):653-63. doi: 10.1042/BJ20031397. Biochem J. 2004. PMID: 14604433 Free PMC article.

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