Eichelbaum M - Search Results

1

Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole.

Saussele T, Burk O, Blievernicht JK, Klein K, Nussler A, Nussler N, Hengstler JG, Eichelbaum M, Schwab M, Zanger UM. Saussele T, et al. Among authors: eichelbaum m. Clin Pharmacol Ther. 2007 Sep;82(3):265-74. doi: 10.1038/sj.clpt.6100138. Epub 2007 Mar 7. Clin Pharmacol Ther. 2007. PMID: 17344806

2

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Lang T, Klein K, Fischer J, Nüssler AK, Neuhaus P, Hofmann U, Eichelbaum M, Schwab M, Zanger UM. Lang T, et al. Among authors: eichelbaum m. Pharmacogenetics. 2001 Jul;11(5):399-415. doi: 10.1097/00008571-200107000-00004. Pharmacogenetics. 2001. PMID: 11470993

3

The impact of thyroid disease on the regulation, expression, and function of ABCB1 (MDR1/P glycoprotein) and consequences for the disposition of digoxin.

Burk O, Brenner SS, Hofmann U, Tegude H, Igel S, Schwab M, Eichelbaum M, Alscher MD. Burk O, et al. Among authors: eichelbaum m. Clin Pharmacol Ther. 2010 Nov;88(5):685-94. doi: 10.1038/clpt.2010.176. Epub 2010 Sep 15. Clin Pharmacol Ther. 2010. PMID: 20844484

4

Functional properties of CYP2D6 1 (wild-type) and CYP2D6 7 (His324Pro) expressed by recombinant baculovirus in insect cells.

Evert B, Eichelbaum M, Haubruck H, Zanger UM. Evert B, et al. Among authors: eichelbaum m. Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar;355(3):309-18. doi: 10.1007/pl00004948. Naunyn Schmiedebergs Arch Pharmacol. 1997. PMID: 9089660

5

Characterization of the major metabolites of verapamil as substrates and inhibitors of P-glycoprotein.

Pauli-Magnus C, von Richter O, Burk O, Ziegler A, Mettang T, Eichelbaum M, Fromm MF. Pauli-Magnus C, et al. Among authors: eichelbaum m. J Pharmacol Exp Ther. 2000 May;293(2):376-82. J Pharmacol Exp Ther. 2000. PMID: 10773005

6

Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6.

Raimundo S, Fischer J, Eichelbaum M, Griese EU, Schwab M, Zanger UM. Raimundo S, et al. Among authors: eichelbaum m. Pharmacogenetics. 2000 Oct;10(7):577-81. doi: 10.1097/00008571-200010000-00001. Pharmacogenetics. 2000. PMID: 11037799

7

High-throughput genotyping of thiopurine S-methyltransferase by denaturing HPLC.

Schaeffeler E, Lang T, Zanger UM, Eichelbaum M, Schwab M. Schaeffeler E, et al. Among authors: eichelbaum m. Clin Chem. 2001 Mar;47(3):548-55. Clin Chem. 2001. PMID: 11238310

8

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.

Geick A, Eichelbaum M, Burk O. Geick A, et al. Among authors: eichelbaum m. J Biol Chem. 2001 May 4;276(18):14581-7. doi: 10.1074/jbc.M010173200. Epub 2001 Jan 31. J Biol Chem. 2001. PMID: 11297522 Free article.

9

Cellular localization and regional distribution of CYP2D6 mRNA and protein expression in human brain.

Siegle I, Fritz P, Eckhardt K, Zanger UM, Eichelbaum M. Siegle I, et al. Among authors: eichelbaum m. Pharmacogenetics. 2001 Apr;11(3):237-45. doi: 10.1097/00008571-200104000-00007. Pharmacogenetics. 2001. PMID: 11337939

10

Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6.

Zanger UM, Fischer J, Raimundo S, Stüven T, Evert BO, Schwab M, Eichelbaum M. Zanger UM, et al. Among authors: eichelbaum m. Pharmacogenetics. 2001 Oct;11(7):573-85. doi: 10.1097/00008571-200110000-00004. Pharmacogenetics. 2001. PMID: 11668217

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