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Mechanism of eIF6 release from the nascent 60S ribosomal subunit.
Weis F, Giudice E, Churcher M, Jin L, Hilcenko C, Wong CC, Traynor D, Kay RR, Warren AJ. Weis F, et al. Among authors: wong cc. Nat Struct Mol Biol. 2015 Nov;22(11):914-9. doi: 10.1038/nsmb.3112. Epub 2015 Oct 19. Nat Struct Mol Biol. 2015. PMID: 26479198 Free PMC article.
eIF6 rebinding dynamically couples ribosome maturation and translation.
Jaako P, Faille A, Tan S, Wong CC, Escudero-Urquijo N, Castro-Hartmann P, Wright P, Hilcenko C, Adams DJ, Warren AJ. Jaako P, et al. Among authors: wong cc. Nat Commun. 2022 Mar 23;13(1):1562. doi: 10.1038/s41467-022-29214-7. Nat Commun. 2022. PMID: 35322020 Free PMC article.
Inactivating CUX1 mutations promote tumorigenesis.
Wong CC, Martincorena I, Rust AG, Rashid M, Alifrangis C, Alexandrov LB, Tiffen JC, Kober C; Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium; Green AR, Massie CE, Nangalia J, Lempidaki S, Döhner H, Döhner K, Bray SJ, McDermott U, Papaemmanuil E, Campbell PJ, Adams DJ. Wong CC, et al. Nat Genet. 2014 Jan;46(1):33-8. doi: 10.1038/ng.2846. Epub 2013 Dec 8. Nat Genet. 2014. PMID: 24316979 Free PMC article.
Population-based analysis of POT1 variants in a cutaneous melanoma case-control cohort.
Simonin-Wilmer I, Ossio R, Leddin EM, Harland M, Pooley KA, Martil de la Garza MG, Obolenski S, Hewinson J, Wong CC, Iyer V, Taylor JC, Newton-Bishop JA, Bishop DT, Cisneros GA, Iles MM, Adams DJ, Robles-Espinoza CD. Simonin-Wilmer I, et al. Among authors: wong cc. J Med Genet. 2023 Jul;60(7):692-696. doi: 10.1136/jmg-2022-108776. Epub 2022 Dec 20. J Med Genet. 2023. PMID: 36539277 Free PMC article.
A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development.
De Franco E, Watson RA, Weninger WJ, Wong CC, Flanagan SE, Caswell R, Green A, Tudor C, Lelliott CJ, Geyer SH, Maurer-Gesek B, Reissig LF, Lango Allen H, Caliebe A, Siebert R, Holterhus PM, Deeb A, Prin F, Hilbrands R, Heimberg H, Ellard S, Hattersley AT, Barroso I. De Franco E, et al. Among authors: wong cc. Am J Hum Genet. 2019 May 2;104(5):985-989. doi: 10.1016/j.ajhg.2019.03.018. Epub 2019 Apr 18. Am J Hum Genet. 2019. PMID: 31006513 Free PMC article.
Gut-liver translocation of pathogen Klebsiella pneumoniae promotes hepatocellular carcinoma in mice.
Wang X, Fang Y, Liang W, Cai Y, Wong CC, Wang J, Wang N, Lau HC, Jiao Y, Zhou X, Ye L, Mo M, Yang T, Fan M, Song L, Zhou H, Zhao Q, Chu ES, Liang M, Liu W, Liu X, Zhang S, Shang H, Wei H, Li X, Xu L, Liao B, Sung JJY, Kuang M, Yu J. Wang X, et al. Among authors: wong cc. Nat Microbiol. 2025 Jan 2. doi: 10.1038/s41564-024-01890-9. Online ahead of print. Nat Microbiol. 2025. PMID: 39747695
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