Karlén A - Search Results

1

Synthesis of a new class of druglike angiotensin II C-terminal mimics with affinity for the AT2 receptor.

Georgsson J, Sköld C, Botros M, Lindeberg G, Nyberg F, Karlén A, Hallberg A, Larhed M. Georgsson J, et al. Among authors: karlen a. J Med Chem. 2007 Apr 5;50(7):1711-5. doi: 10.1021/jm0613469. Epub 2007 Mar 15. J Med Chem. 2007. PMID: 17358051

2

Topography and conformational preferences of 6,7,8,9-tetrahydro-1-hydroxy-N,N-dipropyl-5H-benzocyclohepten-6- ylamin e. A rationale for the dopaminergic inactivity.

Karlén A, Helander A, Kenne L, Hacksell U. Karlén A, et al. J Med Chem. 1989 Apr;32(4):765-74. doi: 10.1021/jm00124a007. J Med Chem. 1989. PMID: 2522990

3

Structural factors of importance for 5-hydroxytryptaminergic activity. Conformational preferences and electrostatic potentials of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and some related agents.

Arvidsson LE, Karlén A, Norinder U, Kenne L, Sundell S, Hacksell U. Arvidsson LE, et al. Among authors: karlen a. J Med Chem. 1988 Jan;31(1):212-21. doi: 10.1021/jm00396a034. J Med Chem. 1988. PMID: 2961887

4

Central dopaminergic and 5-hydroxytryptaminergic effects of C3-methylated derivatives of 8-hydroxy-2-(di-n-propylamino)tetralin.

Mellin C, Björk L, Karlén A, Johansson AM, Sundell S, Kenne L, Nelson DL, Andén NE, Hacksell U. Mellin C, et al. Among authors: karlen a. J Med Chem. 1988 Jun;31(6):1130-40. doi: 10.1021/jm00401a012. J Med Chem. 1988. PMID: 2967376

5

C1- and C3-methyl-substituted derivatives of 7-hydroxy-2-(di-n-propylamino)tetralin: activities at central dopamine receptors.

Johansson AM, Nilsson JL, Karlén A, Hacksell U, Sanchez D, Svensson K, Hjorth S, Carlsson A, Sundell S, Kenne L. Johansson AM, et al. Among authors: karlen a. J Med Chem. 1987 Oct;30(10):1827-37. doi: 10.1021/jm00393a025. J Med Chem. 1987. PMID: 3656358

6

Cyclic HIV-1 protease inhibitors derived from mannitol: synthesis, inhibitory potencies, and computational predictions of binding affinities.

Hultén J, Bonham NM, Nillroth U, Hansson T, Zuccarello G, Bouzide A, Aqvist J, Classon B, Danielson UH, Karlén A, Kvarnström I, Samuelsson B, Hallberg A. Hultén J, et al. Among authors: karlen a. J Med Chem. 1997 Mar 14;40(6):885-97. doi: 10.1021/jm960728j. J Med Chem. 1997. PMID: 9083477

7

Unexpected binding mode of a cyclic sulfamide HIV-1 protease inhibitor.

Bäckbro K, Löwgren S, Osterlund K, Atepo J, Unge T, Hultén J, Bonham NM, Schaal W, Karlén A, Hallberg A. Bäckbro K, et al. Among authors: karlen a. J Med Chem. 1997 Mar 14;40(6):898-902. doi: 10.1021/jm960588d. J Med Chem. 1997. PMID: 9083478

8

Design, synthesis, and biological activities of four angiotensin II receptor ligands with gamma-turn mimetics replacing amino acid residues 3-5.

Schmidt B, Lindman S, Tong W, Lindeberg G, Gogoll A, Lai Z, Thörnwall M, Synnergren B, Nilsson A, Welch CJ, Sohtell M, Westerlund C, Nyberg F, Karlén A, Hallberg A. Schmidt B, et al. Among authors: karlen a. J Med Chem. 1997 Mar 14;40(6):903-19. doi: 10.1021/jm960553d. J Med Chem. 1997. PMID: 9083479

9

Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach.

Winiwarter S, Bonham NM, Ax F, Hallberg A, Lennernäs H, Karlén A. Winiwarter S, et al. Among authors: karlen a. J Med Chem. 1998 Dec 3;41(25):4939-49. doi: 10.1021/jm9810102. J Med Chem. 1998. PMID: 9836611

10

Bicyclic tripeptide mimetics with reverse turn inducing properties.

Johannesson P, Lindeberg G, Tong W, Gogoll A, Karlén A, Hallberg A. Johannesson P, et al. Among authors: karlen a. J Med Chem. 1999 Feb 25;42(4):601-8. doi: 10.1021/jm981077p. J Med Chem. 1999. PMID: 10052967

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