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Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase.
Manfredi MG, Ecsedy JA, Meetze KA, Balani SK, Burenkova O, Chen W, Galvin KM, Hoar KM, Huck JJ, LeRoy PJ, Ray ET, Sells TB, Stringer B, Stroud SG, Vos TJ, Weatherhead GS, Wysong DR, Zhang M, Bolen JB, Claiborne CF. Manfredi MG, et al. Among authors: chen w. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4106-11. doi: 10.1073/pnas.0608798104. Epub 2007 Feb 23. Proc Natl Acad Sci U S A. 2007. PMID: 17360485 Free PMC article.
Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays.
Manfredi MG, Ecsedy JA, Chakravarty A, Silverman L, Zhang M, Hoar KM, Stroud SG, Chen W, Shinde V, Huck JJ, Wysong DR, Janowick DA, Hyer ML, Leroy PJ, Gershman RE, Silva MD, Germanos MS, Bolen JB, Claiborne CF, Sells TB. Manfredi MG, et al. Among authors: chen w. Clin Cancer Res. 2011 Dec 15;17(24):7614-24. doi: 10.1158/1078-0432.CCR-11-1536. Epub 2011 Oct 20. Clin Cancer Res. 2011. PMID: 22016509
Genome-wide siRNA screen for modulators of cell death induced by proteasome inhibitor bortezomib.
Chen S, Blank JL, Peters T, Liu XJ, Rappoli DM, Pickard MD, Menon S, Yu J, Driscoll DL, Lingaraj T, Burkhardt AL, Chen W, Garcia K, Sappal DS, Gray J, Hales P, Leroy PJ, Ringeling J, Rabino C, Spelman JJ, Morgenstern JP, Lightcap ES. Chen S, et al. Among authors: chen w. Cancer Res. 2010 Jun 1;70(11):4318-26. doi: 10.1158/0008-5472.CAN-09-4428. Epub 2010 May 11. Cancer Res. 2010. PMID: 20460535
Exposure-toxicity relationships for tipifarnib in cancer patients.
Perez-Ruixo JJ, Chen W, Zhang S, Hayes S, Chow A. Perez-Ruixo JJ, et al. Among authors: chen w. Br J Clin Pharmacol. 2007 Aug;64(2):219-32. doi: 10.1111/j.1365-2125.2007.02883.x. Epub 2007 Mar 22. Br J Clin Pharmacol. 2007. PMID: 17378913 Free PMC article. Clinical Trial.
Clinical Trial: Precise Administration of Sucralfate Powder in Prevention of Delayed Postpolypectomy Bleeding. A Randomized Controlled Trial.
Chiang HC, Chen PJ, Yang EH, Kuo TL, Hsieh MT, Kang JW, Cheng HC, Chang WL, Chen WY, Chiu HC, Lin MY, Hong TC, Chiang CM, Chen WC, Huang KK, Lu MH, Wu MH, Chen CY, Lin XZ, Chuang CH. Chiang HC, et al. Among authors: chen wy, chen wc. Clin Transl Gastroenterol. 2025 Jan 21. doi: 10.14309/ctg.0000000000000818. Online ahead of print. Clin Transl Gastroenterol. 2025. PMID: 39836033
Single-cell RNA Sequencing Revealed the Immunophenotypic Features of Macrophages in Cardiac Transplants and Uncovered Lgals9 Promoted Their Polarization towards The M2b Subtype.
Zhu Y, Zheng X, Chen C, Xu Y, Fan Y, Tang Z, Zeng Y, Feng C, Zhang H, Chen X, Qi Z, Li T, Peng L, Lin M, Chen W, Peng F, Jiang X, Dai H. Zhu Y, et al. Among authors: chen w. J Leukoc Biol. 2025 Jan 21:qiaf009. doi: 10.1093/jleuko/qiaf009. Online ahead of print. J Leukoc Biol. 2025. PMID: 39835675
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