Morimoto RI - Search Results

1

Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation.

Zourlidou A, Gidalevitz T, Kristiansen M, Landles C, Woodman B, Wells DJ, Latchman DS, de Belleroche J, Tabrizi SJ, Morimoto RI, Bates GP. Zourlidou A, et al. Among authors: morimoto ri. Hum Mol Genet. 2007 May 1;16(9):1078-90. doi: 10.1093/hmg/ddm057. Epub 2007 Mar 14. Hum Mol Genet. 2007. PMID: 17360721

2

A cellular perspective on conformational disease: the role of genetic background and proteostasis networks.

Gidalevitz T, Kikis EA, Morimoto RI. Gidalevitz T, et al. Among authors: morimoto ri. Curr Opin Struct Biol. 2010 Feb;20(1):23-32. doi: 10.1016/j.sbi.2009.11.001. Epub 2010 Jan 5. Curr Opin Struct Biol. 2010. PMID: 20053547 Free PMC article. Review.

3

The stress of protein misfolding: from single cells to multicellular organisms.

Gidalevitz T, Prahlad V, Morimoto RI. Gidalevitz T, et al. Among authors: morimoto ri. Cold Spring Harb Perspect Biol. 2011 Jun 1;3(6):a009704. doi: 10.1101/cshperspect.a009704. Cold Spring Harb Perspect Biol. 2011. PMID: 21536706 Free PMC article. Review.

4

Protein homeostasis in models of aging and age-related conformational disease.

Kikis EA, Gidalevitz T, Morimoto RI. Kikis EA, et al. Among authors: morimoto ri. Adv Exp Med Biol. 2010;694:138-59. doi: 10.1007/978-1-4419-7002-2_11. Adv Exp Med Biol. 2010. PMID: 20886762 Free PMC article. Review.

5

Destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicity.

Gidalevitz T, Krupinski T, Garcia S, Morimoto RI. Gidalevitz T, et al. Among authors: morimoto ri. PLoS Genet. 2009 Mar;5(3):e1000399. doi: 10.1371/journal.pgen.1000399. Epub 2009 Mar 6. PLoS Genet. 2009. PMID: 19266020 Free PMC article.

6

Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegans model for polyglutamine disease.

Gidalevitz T, Wang N, Deravaj T, Alexander-Floyd J, Morimoto RI. Gidalevitz T, et al. Among authors: morimoto ri. BMC Biol. 2013 Sep 30;11:100. doi: 10.1186/1741-7007-11-100. BMC Biol. 2013. PMID: 24079614 Free PMC article.

7

Progressive disruption of cellular protein folding in models of polyglutamine diseases.

Gidalevitz T, Ben-Zvi A, Ho KH, Brignull HR, Morimoto RI. Gidalevitz T, et al. Among authors: morimoto ri. Science. 2006 Mar 10;311(5766):1471-4. doi: 10.1126/science.1124514. Epub 2006 Feb 9. Science. 2006. PMID: 16469881

8

Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule.

Trott A, West JD, Klaić L, Westerheide SD, Silverman RB, Morimoto RI, Morano KA. Trott A, et al. Among authors: morimoto ri. Mol Biol Cell. 2008 Mar;19(3):1104-12. doi: 10.1091/mbc.e07-10-1004. Epub 2008 Jan 16. Mol Biol Cell. 2008. PMID: 18199679 Free PMC article.

9

Huntington's disease: underlying molecular mechanisms and emerging concepts.

Labbadia J, Morimoto RI. Labbadia J, et al. Among authors: morimoto ri. Trends Biochem Sci. 2013 Aug;38(8):378-85. doi: 10.1016/j.tibs.2013.05.003. Epub 2013 Jun 12. Trends Biochem Sci. 2013. PMID: 23768628 Free PMC article. Review.

10

Heat shock response activation exacerbates inclusion body formation in a cellular model of Huntington disease.

Bersuker K, Hipp MS, Calamini B, Morimoto RI, Kopito RR. Bersuker K, et al. Among authors: morimoto ri. J Biol Chem. 2013 Aug 16;288(33):23633-8. doi: 10.1074/jbc.C113.481945. Epub 2013 Jul 9. J Biol Chem. 2013. PMID: 23839939 Free PMC article.

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