Small DS - Search Results

1

Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently.

Farid NA, Payne CD, Small DS, Winters KJ, Ernest CS 2nd, Brandt JT, Darstein C, Jakubowski JA, Salazar DE. Farid NA, et al. Among authors: small ds. Clin Pharmacol Ther. 2007 May;81(5):735-41. doi: 10.1038/sj.clpt.6100139. Epub 2007 Mar 14. Clin Pharmacol Ther. 2007. PMID: 17361128 Clinical Trial.

2

Effect of rifampin on the pharmacokinetics and pharmacodynamics of prasugrel in healthy male subjects.

Farid NA, Jakubowski JA, Payne CD, Li YG, Jin Y, Ernest II CS, Winters KJ, Brandt JT, Salazar DE, Small DS. Farid NA, et al. Among authors: small ds. Curr Med Res Opin. 2009 Aug;25(8):1821-9. doi: 10.1185/03007990903018360. Curr Med Res Opin. 2009. PMID: 19530977 Clinical Trial.

3

Pharmacokinetics and pharmacodynamics of prasugrel in subjects with moderate liver disease.

Small DS, Farid NA, Li YG, Ernest CS 2nd, Winters KJ, Salazar DE, Payne CD. Small DS, et al. J Clin Pharm Ther. 2009 Oct;34(5):575-83. doi: 10.1111/j.1365-2710.2009.01067.x. J Clin Pharm Ther. 2009. PMID: 19744013

4

Prasugrel pharmacokinetics and pharmacodynamics in subjects with moderate renal impairment and end-stage renal disease.

Small DS, Wrishko RE, Ernest CS 2nd, Ni L, Winters KJ, Farid NA, Li YG, Brandt JT, Salazar DE, Borel AG, Kles KA, Payne CD. Small DS, et al. J Clin Pharm Ther. 2009 Oct;34(5):585-94. doi: 10.1111/j.1365-2710.2009.01068.x. J Clin Pharm Ther. 2009. PMID: 19744014

5

Population pharmacokinetic analyses to evaluate the influence of intrinsic and extrinsic factors on exposure of prasugrel active metabolite in TRITON-TIMI 38.

Wrishko RE, Ernest CS 2nd, Small DS, Li YG, Weerakkody GJ, Riesmeyer JR, Macias WL, Rohatagi S, Salazar DE, Antman EM, Wiviott SD, Braunwald E, Ni L. Wrishko RE, et al. Among authors: small ds. J Clin Pharmacol. 2009 Aug;49(8):984-98. doi: 10.1177/0091270009337942. Epub 2009 Jun 22. J Clin Pharmacol. 2009. PMID: 19546250

6

Inhibition of platelet aggregation with prasugrel and clopidogrel: an integrated analysis in 846 subjects.

Li YG, Ni L, Brandt JT, Small DS, Payne CD, Ernest CS 2nd, Rohatagi S, Farid NA, Jakubowski JA, Winters KJ. Li YG, et al. Among authors: small ds. Platelets. 2009 Aug;20(5):316-27. doi: 10.1080/09537100903046317. Platelets. 2009. PMID: 19637095 Free article.

7

Effect of age on the pharmacokinetics and pharmacodynamics of prasugrel during multiple dosing: an open-label, single-sequence, clinical trial.

Small DS, Wrishko RE, Ernest CS 2nd, Ni L, Winters KJ, Farid NA, Li YG, Salazar DE, Payne CD. Small DS, et al. Drugs Aging. 2009;26(9):781-90. doi: 10.2165/11315780-000000000-00000. Drugs Aging. 2009. PMID: 19728751 Clinical Trial.

8

The pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects.

Small DS, Kothare P, Yuen E, Lachno DR, Li YG, Winters KJ, Farid NA, Ni L, Jakubowski JA, Salazar DE, Thieu VT, Payne CD. Small DS, et al. Eur J Clin Pharmacol. 2010 Feb;66(2):127-35. doi: 10.1007/s00228-009-0737-1. Epub 2009 Nov 4. Eur J Clin Pharmacol. 2010. PMID: 19888568 Clinical Trial.

9

Pharmacodynamics and pharmacokinetics of single doses of prasugrel 30 mg and clopidogrel 300 mg in healthy Chinese and white volunteers: an open-label trial.

Small DS, Payne CD, Kothare P, Yuen E, Natanegara F, Teng Loh M, Jakubowski JA, Richard Lachno D, Li YG, Winters KJ, Farid NA, Ni L, Salazar DE, Tomlin M, Kelly R. Small DS, et al. Clin Ther. 2010 Feb;32(2):365-79. doi: 10.1016/j.clinthera.2010.02.015. Clin Ther. 2010. PMID: 20206794 Clinical Trial.

10

A comparison of the VerifyNow P2Y12 point-of-care device and light transmission aggregometry to monitor platelet function with prasugrel and clopidogrel: an integrated analysis.

Jakubowski JA, Li YG, Small DS, Payne CD, Tomlin ME, Luo J, Winters KJ. Jakubowski JA, et al. Among authors: small ds. J Cardiovasc Pharmacol. 2010 Jul;56(1):29-37. doi: 10.1097/FJC.0b013e3181dd0ec2. J Cardiovasc Pharmacol. 2010. PMID: 20386460

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