Fluiter K - Search Results

1

Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo.

Mook OR, Baas F, de Wissel MB, Fluiter K. Mook OR, et al. Among authors: fluiter k. Mol Cancer Ther. 2007 Mar;6(3):833-43. doi: 10.1158/1535-7163.MCT-06-0195. Mol Cancer Ther. 2007. PMID: 17363479 Free article.

2

Polymorphisms in the large subunit of human RNA polymerase II as target for allele-specific inhibition.

ten Asbroek AL, Fluiter K, van Groenigen M, Nooij M, Baas F. ten Asbroek AL, et al. Among authors: fluiter k. Nucleic Acids Res. 2000 Mar 1;28(5):1133-8. doi: 10.1093/nar/28.5.1133. Nucleic Acids Res. 2000. PMID: 10666454 Free PMC article.

3

Tumor genotype-specific growth inhibition in vivo by antisense oligonucleotides against a polymorphic site of the large subunit of human RNA polymerase II.

Fluiter K, ten Asbroek AL, van Groenigen M, Nooij M, Aalders MC, Baas F. Fluiter K, et al. Cancer Res. 2002 Apr 1;62(7):2024-8. Cancer Res. 2002. PMID: 11929820

4

In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides.

Fluiter K, ten Asbroek AL, de Wissel MB, Jakobs ME, Wissenbach M, Olsson H, Olsen O, Oerum H, Baas F. Fluiter K, et al. Nucleic Acids Res. 2003 Feb 1;31(3):953-62. doi: 10.1093/nar/gkg185. Nucleic Acids Res. 2003. PMID: 12560491 Free PMC article.

5

Killing cancer by targeting genes that cancer cells have lost: allele-specific inhibition, a novel approach to the treatment of genetic disorders.

Fluiter K, Housman D, Ten Asbroek AL, Baas F. Fluiter K, et al. Cell Mol Life Sci. 2003 May;60(5):834-43. doi: 10.1007/s00018-003-3043-6. Cell Mol Life Sci. 2003. PMID: 12827273 Free PMC article. Review.

6

On the in vitro and in vivo properties of four locked nucleic acid nucleotides incorporated into an anti-H-Ras antisense oligonucleotide.

Fluiter K, Frieden M, Vreijling J, Rosenbohm C, De Wissel MB, Christensen SM, Koch T, Ørum H, Baas F. Fluiter K, et al. Chembiochem. 2005 Jun;6(6):1104-9. doi: 10.1002/cbic.200400419. Chembiochem. 2005. PMID: 15861430

7

Evaluation of LNA-modified DNAzymes targeting a single nucleotide polymorphism in the large subunit of RNA polymerase II.

Fluiter K, Frieden M, Vreijling J, Koch T, Baas F. Fluiter K, et al. Oligonucleotides. 2005 Dec;15(4):246-54. doi: 10.1089/oli.2005.15.246. Oligonucleotides. 2005. PMID: 16396619

8

Allele-specific cancer cell killing in vitro and in vivo targeting a single-nucleotide polymorphism in POLR2A.

Mook OR, Baas F, de Wissel MB, Fluiter K. Mook OR, et al. Among authors: fluiter k. Cancer Gene Ther. 2009 Jun;16(6):532-8. doi: 10.1038/cgt.2008.104. Epub 2009 Jan 23. Cancer Gene Ther. 2009. PMID: 19165236

9

The therapeutic potential of LNA-modified siRNAs: reduction of off-target effects by chemical modification of the siRNA sequence.

Fluiter K, Mook OR, Baas F. Fluiter K, et al. Methods Mol Biol. 2009;487:189-203. doi: 10.1007/978-1-60327-547-7_9. Methods Mol Biol. 2009. PMID: 19301648 Review.

10

Filling the gap in LNA antisense oligo gapmers: the effects of unlocked nucleic acid (UNA) and 4'-C-hydroxymethyl-DNA modifications on RNase H recruitment and efficacy of an LNA gapmer.

Fluiter K, Mook OR, Vreijling J, Langkjaer N, Højland T, Wengel J, Baas F. Fluiter K, et al. Mol Biosyst. 2009 Aug;5(8):838-43. doi: 10.1039/b903922h. Epub 2009 May 19. Mol Biosyst. 2009. PMID: 19603119

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