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BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl.
Hemmeryckx B, Reichert A, Watanabe M, Kaartinen V, de Jong R, Pattengale PK, Groffen J, Heisterkamp N. Hemmeryckx B, et al. Among authors: pattengale pk. Oncogene. 2002 May 9;21(20):3225-31. doi: 10.1038/sj.onc.1205452. Oncogene. 2002. PMID: 12082638
Human bcr-abl gene has a lethal effect on embryogenesis.
Heisterkamp N, Jenster G, Kioussis D, Pattengale PK, Groffen J. Heisterkamp N, et al. Among authors: pattengale pk. Transgenic Res. 1991 Dec;1(1):45-53. doi: 10.1007/BF02512996. Transgenic Res. 1991. PMID: 1726940
Acute leukaemia in bcr/abl transgenic mice.
Heisterkamp N, Jenster G, ten Hoeve J, Zovich D, Pattengale PK, Groffen J. Heisterkamp N, et al. Among authors: pattengale pk. Nature. 1990 Mar 15;344(6263):251-3. doi: 10.1038/344251a0. Nature. 1990. PMID: 2179728
Reduced oncogenicity of p190 Bcr/Abl F-actin-binding domain mutants.
Heisterkamp N, Voncken JW, Senadheera D, Gonzalez-Gomez I, Reichert A, Haataja L, Reinikainen A, Pattengale PK, Groffen J. Heisterkamp N, et al. Among authors: pattengale pk. Blood. 2000 Sep 15;96(6):2226-32. Blood. 2000. PMID: 10979970 Free article.
Crkl enhances leukemogenesis in BCR/ABL P190 transgenic mice.
Hemmeryckx B, van Wijk A, Reichert A, Kaartinen V, de Jong R, Pattengale PK, Gonzalez-Gomez I, Groffen J, Heisterkamp N. Hemmeryckx B, et al. Among authors: pattengale pk. Cancer Res. 2001 Feb 15;61(4):1398-405. Cancer Res. 2001. PMID: 11245441
Increased neutrophil respiratory burst in bcr-null mutants.
Voncken JW, van Schaick H, Kaartinen V, Deemer K, Coates T, Landing B, Pattengale P, Dorseuil O, Bokoch GM, Groffen J, et al. Voncken JW, et al. Among authors: pattengale p. Cell. 1995 Mar 10;80(5):719-28. doi: 10.1016/0092-8674(95)90350-x. Cell. 1995. PMID: 7889565 Free article.
101 results