Chu CK - Search Results

1

D- and L-2',3'-didehydro-2',3'-dideoxy-3'-fluoro-carbocyclic nucleosides: synthesis, anti-HIV activity and mechanism of resistance.

Wang J, Jin Y, Rapp KL, Schinazi RF, Chu CK. Wang J, et al. Among authors: chu ck. J Med Chem. 2007 Apr 19;50(8):1828-39. doi: 10.1021/jm061304k. Epub 2007 Mar 21. J Med Chem. 2007. PMID: 17373782 Free PMC article.

2

Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes.

Schinazi RF, Chu CK, Peck A, McMillan A, Mathis R, Cannon D, Jeong LS, Beach JW, Choi WB, Yeola S, et al. Schinazi RF, et al. Among authors: chu ck. Antimicrob Agents Chemother. 1992 Mar;36(3):672-6. doi: 10.1128/AAC.36.3.672. Antimicrob Agents Chemother. 1992. PMID: 1320365 Free PMC article.

3

Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication.

Chang CN, Doong SL, Zhou JH, Beach JW, Jeong LS, Chu CK, Tsai CH, Cheng YC, Liotta D, Schinazi R. Chang CN, et al. Among authors: chu ck. J Biol Chem. 1992 Jul 15;267(20):13938-42. J Biol Chem. 1992. PMID: 1321132 Free article.

4

Catabolic disposition of 3'-azido-2',3'-dideoxyuridine in hepatocytes with evidence of azido reduction being a general catabolic pathway of 3'-azido-2',3'-dideoxynucleosides.

Cretton EM, Xie MY, Goudgaon NM, Schinazi RF, Chu CK, Sommadossi JP. Cretton EM, et al. Among authors: chu ck. Biochem Pharmacol. 1992 Sep 1;44(5):973-80. doi: 10.1016/0006-2952(92)90130-b. Biochem Pharmacol. 1992. PMID: 1326966

5

Comparison of cytotoxicity of the (-)- and (+)-enantiomer of 2',3'-dideoxy-3'-thiacytidine in normal human bone marrow progenitor cells.

Sommadossi JP, Schinazi RF, Chu CK, Xie MY. Sommadossi JP, et al. Among authors: chu ck. Biochem Pharmacol. 1992 Nov 17;44(10):1921-5. doi: 10.1016/0006-2952(92)90093-x. Biochem Pharmacol. 1992. PMID: 1333199

6

Asymmetric synthesis of 1,3-dioxolane-pyrimidine nucleosides and their anti-HIV activity.

Kim HO, Ahn SK, Alves AJ, Beach JW, Jeong LS, Choi BG, Van Roey P, Schinazi RF, Chu CK. Kim HO, et al. Among authors: chu ck. J Med Chem. 1992 May 29;35(11):1987-95. doi: 10.1021/jm00089a007. J Med Chem. 1992. PMID: 1597854

7

Anthraquinones as a new class of antiviral agents against human immunodeficiency virus.

Schinazi RF, Chu CK, Babu JR, Oswald BJ, Saalmann V, Cannon DL, Eriksson BF, Nasr M. Schinazi RF, et al. Among authors: chu ck. Antiviral Res. 1990 May;13(5):265-72. doi: 10.1016/0166-3542(90)90071-e. Antiviral Res. 1990. PMID: 1697740

8

Synthesis and anti-human immunodeficiency virus (HIV-1) activity of 3'-deoxy-3'-(triazol-1-yl)thymidines and 2',3'-dideoxy-3'-(triazol-1-yl)uridines and inhibition of reverse transcriptase by their 5'-triphosphates.

Hirota K, Hosono H, Kitade Y, Maki Y, Chu CK, Schinazi RF, Nakane H, Ono K. Hirota K, et al. Among authors: chu ck. Chem Pharm Bull (Tokyo). 1990 Sep;38(9):2597-601. doi: 10.1248/cpb.38.2597. Chem Pharm Bull (Tokyo). 1990. PMID: 1704819

9

Correlation of molecular conformation and activity of reverse transcriptase inhibitors.

Van Roey P, Taylor EW, Chu CK, Schinazi RF. Van Roey P, et al. Among authors: chu ck. Ann N Y Acad Sci. 1990;616:29-40. doi: 10.1111/j.1749-6632.1990.tb17825.x. Ann N Y Acad Sci. 1990. PMID: 1706572 Review. No abstract available.

10

Antiretroviral activity, biochemistry, and pharmacokinetics of 3'-azido-2',3'-dideoxy-5-methylcytidine.

Schinazi RF, Chu CK, Eriksson BF, Sommadossi JP, Doshi KJ, Boudinot FD, Oswald B, McClure HM. Schinazi RF, et al. Among authors: chu ck. Ann N Y Acad Sci. 1990;616:385-97. doi: 10.1111/j.1749-6632.1990.tb17858.x. Ann N Y Acad Sci. 1990. PMID: 1706574 Review.

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