Otey CR - Search Results

1

Diversification of catalytic function in a synthetic family of chimeric cytochrome p450s.

Landwehr M, Carbone M, Otey CR, Li Y, Arnold FH. Landwehr M, et al. Among authors: otey cr. Chem Biol. 2007 Mar;14(3):269-78. doi: 10.1016/j.chembiol.2007.01.009. Chem Biol. 2007. PMID: 17379142 Free PMC article.

2

Functional evolution and structural conservation in chimeric cytochromes p450: calibrating a structure-guided approach.

Otey CR, Silberg JJ, Voigt CA, Endelman JB, Bandara G, Arnold FH. Otey CR, et al. Chem Biol. 2004 Mar;11(3):309-18. doi: 10.1016/j.chembiol.2004.02.018. Chem Biol. 2004. PMID: 15123260

3

Structure-guided recombination creates an artificial family of cytochromes P450.

Otey CR, Landwehr M, Endelman JB, Hiraga K, Bloom JD, Arnold FH. Otey CR, et al. PLoS Biol. 2006 May;4(5):e112. doi: 10.1371/journal.pbio.0040112. Epub 2006 Apr 11. PLoS Biol. 2006. PMID: 16594730 Free PMC article.

4

Evolving strategies for enzyme engineering.

Bloom JD, Meyer MM, Meinhold P, Otey CR, MacMillan D, Arnold FH. Bloom JD, et al. Among authors: otey cr. Curr Opin Struct Biol. 2005 Aug;15(4):447-52. doi: 10.1016/j.sbi.2005.06.004. Curr Opin Struct Biol. 2005. PMID: 16006119 Review.

5

Preparation of human metabolites of propranolol using laboratory-evolved bacterial cytochromes P450.

Otey CR, Bandara G, Lalonde J, Takahashi K, Arnold FH. Otey CR, et al. Biotechnol Bioeng. 2006 Feb 20;93(3):494-9. doi: 10.1002/bit.20744. Biotechnol Bioeng. 2006. PMID: 16224788

6

Protein stability promotes evolvability.

Bloom JD, Labthavikul ST, Otey CR, Arnold FH. Bloom JD, et al. Among authors: otey cr. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5869-74. doi: 10.1073/pnas.0510098103. Epub 2006 Mar 31. Proc Natl Acad Sci U S A. 2006. PMID: 16581913 Free PMC article.

7

Enantioselective alpha-hydroxylation of 2-arylacetic acid derivatives and buspirone catalyzed by engineered cytochrome P450 BM-3.

Landwehr M, Hochrein L, Otey CR, Kasrayan A, Bäckvall JE, Arnold FH. Landwehr M, et al. Among authors: otey cr. J Am Chem Soc. 2006 May 10;128(18):6058-9. doi: 10.1021/ja061261x. J Am Chem Soc. 2006. PMID: 16669674 Free PMC article.

8

Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine.

Shapiro MG, Westmeyer GG, Romero PA, Szablowski JO, Küster B, Shah A, Otey CR, Langer R, Arnold FH, Jasanoff A. Shapiro MG, et al. Among authors: otey cr. Nat Biotechnol. 2010 Mar;28(3):264-70. doi: 10.1038/nbt.1609. Epub 2010 Feb 28. Nat Biotechnol. 2010. PMID: 20190737 Free PMC article.

9

Cost-effective whole-cell assay for laboratory evolution of hydroxylases in Escherichia coli.

Schwaneberg U, Otey C, Cirino PC, Farinas E, Arnold FH. Schwaneberg U, et al. J Biomol Screen. 2001 Apr;6(2):111-7. doi: 10.1177/108705710100600207. J Biomol Screen. 2001. PMID: 11689105

10

High-throughput carbon monoxide binding assay for cytochromes p450.

Otey CR. Otey CR. Methods Mol Biol. 2003;230:137-9. doi: 10.1385/1-59259-396-8:137. Methods Mol Biol. 2003. PMID: 12824576 No abstract available.

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