Karim A - Search Results

1

Age and gender effects on the pharmacokinetics and pharmacodynamics of ramelteon, a hypnotic agent acting via melatonin receptors MT1 and MT2.

Greenblatt DJ, Harmatz JS, Karim A. Greenblatt DJ, et al. Among authors: karim a. J Clin Pharmacol. 2007 Apr;47(4):485-96. doi: 10.1177/0091270006298602. J Clin Pharmacol. 2007. PMID: 17389558 Clinical Trial.

2

Disposition kinetics and tolerance of escalating single doses of ramelteon, a high-affinity MT1 and MT2 melatonin receptor agonist indicated for treatment of insomnia.

Karim A, Tolbert D, Cao C. Karim A, et al. J Clin Pharmacol. 2006 Feb;46(2):140-8. doi: 10.1177/0091270005283461. J Clin Pharmacol. 2006. PMID: 16432265 Clinical Trial.

3

Evaluation of the impact of UGT polymorphism on the pharmacokinetics and pharmacodynamics of the novel PPAR agonist sipoglitazar.

Stringer F, Ploeger BA, DeJongh J, Scott G, Urquhart R, Karim A, Danhof M. Stringer F, et al. Among authors: karim a. J Clin Pharmacol. 2013 Mar;53(3):256-63. doi: 10.1177/0091270012447121. Epub 2013 Jan 24. J Clin Pharmacol. 2013. PMID: 23444281 Clinical Trial.

4

Replicate study design in bioequivalency assessment, pros and cons: bioavailabilities of the antidiabetic drugs pioglitazone and glimepiride present in a fixed-dose combination formulation.

Karim A, Zhao Z, Slater M, Bradford D, Schuster J, Laurent A. Karim A, et al. J Clin Pharmacol. 2007 Jul;47(7):806-16. doi: 10.1177/0091270007300954. Epub 2007 Apr 26. J Clin Pharmacol. 2007. PMID: 17463215 Clinical Trial.

5

Oral antidiabetic drugs: bioavailability assessment of fixed-dose combination tablets of pioglitazone and metformin. Effect of body weight, gender, and race on systemic exposures of each drug.

Karim A, Slater M, Bradford D, Schwartz L, Zhao Z, Cao C, Laurent A. Karim A, et al. J Clin Pharmacol. 2007 Jan;47(1):37-47. doi: 10.1177/0091270006293755. J Clin Pharmacol. 2007. PMID: 17192500 Clinical Trial.

6

Oral antidiabetic drugs: effect of food on absorption of pioglitazone and metformin from a fixed-dose combination tablet.

Karim A, Slater M, Bradford D, Schwartz L, Laurent A. Karim A, et al. J Clin Pharmacol. 2007 Jan;47(1):48-55. doi: 10.1177/0091270006293756. J Clin Pharmacol. 2007. PMID: 17192501 Clinical Trial.

7

Single-Center Evaluation of the Pharmacokinetics and Safety of the Angiotensin II Receptor Antagonist Azilsartan Medoxomil in Mild to Moderate Hepatic Impairment.

Dudkowski C, Karim A, Zhao Z, Alonso AB, Garg D, Preston RA. Dudkowski C, et al. Among authors: karim a. J Clin Pharmacol. 2018 Jan;58(1):48-56. doi: 10.1002/jcph.970. Epub 2017 Jul 27. J Clin Pharmacol. 2018. PMID: 28750149 Free PMC article. Clinical Trial.

8

Pharmacokinetics, pharmacodynamics, and tolerability of single increasing doses of the dipeptidyl peptidase-4 inhibitor alogliptin in healthy male subjects.

Christopher R, Covington P, Davenport M, Fleck P, Mekki QA, Wann ER, Karim A. Christopher R, et al. Among authors: karim a. Clin Ther. 2008 Mar;30(3):513-27. doi: 10.1016/j.clinthera.2008.03.005. Clin Ther. 2008. PMID: 18405789 Clinical Trial.

9

Single-center evaluation of the single-dose pharmacokinetics of the angiotensin II receptor antagonist azilsartan medoxomil in renal impairment.

Preston RA, Karim A, Dudkowski C, Zhao Z, Garg D, Lenz O, Sica DA. Preston RA, et al. Among authors: karim a. Clin Pharmacokinet. 2013 May;52(5):347-58. doi: 10.1007/s40262-013-0044-y. Clin Pharmacokinet. 2013. PMID: 23575872 Clinical Trial.

10

Coadministration of pioglitazone or glyburide and alogliptin: pharmacokinetic drug interaction assessment in healthy participants.

Karim A, Laurent A, Munsaka M, Wann E, Fleck P, Mekki Q. Karim A, et al. J Clin Pharmacol. 2009 Oct;49(10):1210-9. doi: 10.1177/0091270009338938. Epub 2009 Jul 21. J Clin Pharmacol. 2009. PMID: 19622714 Clinical Trial.

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