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The alpha-methylene-gamma-butyrolactone moiety in dehydrocostus lactone is responsible for cytoprotective heme oxygenase-1 expression through activation of the nuclear factor E2-related factor 2 in HepG2 cells.
Jeong GS, Pae HO, Jeong SO, Kim YC, Kwon TO, Lee HS, Kim NS, Park SD, Chung HT. Jeong GS, et al. Among authors: kwon to. Eur J Pharmacol. 2007 Jun 22;565(1-3):37-44. doi: 10.1016/j.ejphar.2007.02.053. Epub 2007 Mar 7. Eur J Pharmacol. 2007. PMID: 17391667
Okanin, a chalcone found in the genus Bidens, and 3-penten-2-one inhibit inducible nitric oxide synthase expression via heme oxygenase-1 induction in RAW264.7 macrophages activated with lipopolysaccharide.
Kil JS, Son Y, Cheong YK, Kim NH, Jeong HJ, Kwon JW, Lee EJ, Kwon TO, Chung HT, Pae HO. Kil JS, et al. Among authors: kwon to. J Clin Biochem Nutr. 2012 Jan;50(1):53-8. doi: 10.3164/jcbn.11-30. Epub 2011 Dec 15. J Clin Biochem Nutr. 2012. PMID: 22247601 Free PMC article.
43 results