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The loss of mdm2 induces p53-mediated apoptosis.
de Rozieres S, Maya R, Oren M, Lozano G. de Rozieres S, et al. Among authors: lozano g. Oncogene. 2000 Mar 23;19(13):1691-7. doi: 10.1038/sj.onc.1203468. Oncogene. 2000. PMID: 10763826
Loss of Mdm4 results in p53-dependent dilated cardiomyopathy.
Xiong S, Van Pelt CS, Elizondo-Fraire AC, Fernandez-Garcia B, Lozano G. Xiong S, et al. Among authors: lozano g. Circulation. 2007 Jun 12;115(23):2925-30. doi: 10.1161/CIRCULATIONAHA.107.689901. Epub 2007 May 28. Circulation. 2007. PMID: 17533180
Mdm2 and Mdm4 loss regulates distinct p53 activities.
Barboza JA, Iwakuma T, Terzian T, El-Naggar AK, Lozano G. Barboza JA, et al. Among authors: lozano g. Mol Cancer Res. 2008 Jun;6(6):947-54. doi: 10.1158/1541-7786.MCR-07-2079. Mol Cancer Res. 2008. PMID: 18567799 Free PMC article.
510 results