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Page 1
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers.
De Felice FG, Wu D, Lambert MP, Fernandez SJ, Velasco PT, Lacor PN, Bigio EH, Jerecic J, Acton PJ, Shughrue PJ, Chen-Dodson E, Kinney GG, Klein WL. De Felice FG, et al. Among authors: kinney gg. Neurobiol Aging. 2008 Sep;29(9):1334-47. doi: 10.1016/j.neurobiolaging.2007.02.029. Epub 2007 Apr 2. Neurobiol Aging. 2008. PMID: 17403556 Free PMC article.
Anti-ADDL antibodies differentially block oligomer binding to hippocampal neurons.
Shughrue PJ, Acton PJ, Breese RS, Zhao WQ, Chen-Dodson E, Hepler RW, Wolfe AL, Matthews M, Heidecker GJ, Joyce JG, Villarreal SA, Kinney GG. Shughrue PJ, et al. Among authors: kinney gg. Neurobiol Aging. 2010 Feb;31(2):189-202. doi: 10.1016/j.neurobiolaging.2008.04.003. Neurobiol Aging. 2010. PMID: 18486276
Inhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid beta oligomer-induced synaptic disruption.
Zhao WQ, Santini F, Breese R, Ross D, Zhang XD, Stone DJ, Ferrer M, Townsend M, Wolfe AL, Seager MA, Kinney GG, Shughrue PJ, Ray WJ. Zhao WQ, et al. Among authors: kinney gg. J Biol Chem. 2010 Mar 5;285(10):7619-32. doi: 10.1074/jbc.M109.057182. Epub 2009 Dec 23. J Biol Chem. 2010. PMID: 20032460 Free PMC article.
Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation.
Ma L, Seager MA, Wittmann M, Jacobson M, Bickel D, Burno M, Jones K, Graufelds VK, Xu G, Pearson M, McCampbell A, Gaspar R, Shughrue P, Danziger A, Regan C, Flick R, Pascarella D, Garson S, Doran S, Kreatsoulas C, Veng L, Lindsley CW, Shipe W, Kuduk S, Sur C, Kinney G, Seabrook GR, Ray WJ. Ma L, et al. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15950-5. doi: 10.1073/pnas.0900903106. Epub 2009 Aug 26. Proc Natl Acad Sci U S A. 2009. PMID: 19717450 Free PMC article.
60 results