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Page 1
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
Graham RR, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, Baechler EC, Plenge RM, Koeuth T, Ortmann WA, Hom G, Bauer JW, Gillett C, Burtt N, Cunninghame Graham DS, Onofrio R, Petri M, Gunnarsson I, Svenungsson E, Rönnblom L, Nordmark G, Gregersen PK, Moser K, Gaffney PM, Criswell LA, Vyse TJ, Syvänen AC, Bohjanen PR, Daly MJ, Behrens TW, Altshuler D. Graham RR, et al. Among authors: gunnarsson i. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6758-63. doi: 10.1073/pnas.0701266104. Epub 2007 Apr 5. Proc Natl Acad Sci U S A. 2007. PMID: 17412832 Free PMC article.
Association analysis with microsatellite and SNP markers does not support the involvement of BCL-2 in systemic lupus erythematosus in Mexican and Swedish patients and their families.
Johansson C, Castillejo-López C, Johanneson B, Svenungsson E, Gunnarsson I, Frostegård J, Sturfelt G, Truedsson L, Löfström B, Alcocer-Varela J, Lundberg I, Gyllensten UB, Alarcón-Segovia D, Alarcón-Riquelme ME. Johansson C, et al. Among authors: gunnarsson i. Genes Immun. 2000 Aug;1(6):380-5. doi: 10.1038/sj.gene.6363688. Genes Immun. 2000. PMID: 11196685
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans.
Prokunina L, Castillejo-López C, Oberg F, Gunnarsson I, Berg L, Magnusson V, Brookes AJ, Tentler D, Kristjansdóttir H, Gröndal G, Bolstad AI, Svenungsson E, Lundberg I, Sturfelt G, Jönssen A, Truedsson L, Lima G, Alcocer-Varela J, Jonsson R, Gyllensten UB, Harley JB, Alarcón-Segovia D, Steinsson K, Alarcón-Riquelme ME. Prokunina L, et al. Among authors: gunnarsson i. Nat Genet. 2002 Dec;32(4):666-9. doi: 10.1038/ng1020. Epub 2002 Oct 28. Nat Genet. 2002. PMID: 12402038
Elevated triglycerides and low levels of high-density lipoprotein as markers of disease activity in association with up-regulation of the tumor necrosis factor alpha/tumor necrosis factor receptor system in systemic lupus erythematosus.
Svenungsson E, Gunnarsson I, Fei GZ, Lundberg IE, Klareskog L, Frostegård J. Svenungsson E, et al. Among authors: gunnarsson i. Arthritis Rheum. 2003 Sep;48(9):2533-40. doi: 10.1002/art.11264. Arthritis Rheum. 2003. PMID: 13130473 Free article.
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus.
Sigurdsson S, Göring HH, Kristjansdottir G, Milani L, Nordmark G, Sandling JK, Eloranta ML, Feng D, Sangster-Guity N, Gunnarsson I, Svenungsson E, Sturfelt G, Jönsen A, Truedsson L, Barnes BJ, Alm G, Rönnblom L, Syvänen AC. Sigurdsson S, et al. Among authors: gunnarsson i. Hum Mol Genet. 2008 Mar 15;17(6):872-81. doi: 10.1093/hmg/ddm359. Epub 2007 Dec 6. Hum Mol Genet. 2008. PMID: 18063667
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S, Lee AT, Chung SA, Ferreira RC, Pant PV, Ballinger DG, Kosoy R, Demirci FY, Kamboh MI, Kao AH, Tian C, Gunnarsson I, Bengtsson AA, Rantapää-Dahlqvist S, Petri M, Manzi S, Seldin MF, Rönnblom L, Syvänen AC, Criswell LA, Gregersen PK, Behrens TW. Hom G, et al. Among authors: gunnarsson i. N Engl J Med. 2008 Feb 28;358(9):900-9. doi: 10.1056/NEJMoa0707865. Epub 2008 Jan 20. N Engl J Med. 2008. PMID: 18204098 Free article.
245 results