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Page 1
SAR, pharmacokinetics, safety, and efficacy of glucokinase activating 2-(4-sulfonylphenyl)-N-thiazol-2-ylacetamides: discovery of PSN-GK1.
Bertram LS, Black D, Briner PH, Chatfield R, Cooke A, Fyfe MC, Murray PJ, Naud F, Nawano M, Procter MJ, Rakipovski G, Rasamison CM, Reynet C, Schofield KL, Shah VK, Spindler F, Taylor A, Turton R, Williams GM, Wong-Kai-In P, Yasuda K. Bertram LS, et al. Among authors: procter mj. J Med Chem. 2008 Jul 24;51(14):4340-5. doi: 10.1021/jm8003202. Epub 2008 Jun 28. J Med Chem. 2008. PMID: 18588279
Glucokinase-activating ureas.
Castelhano AL, Dong H, Fyfe MC, Gardner LS, Kamikozawa Y, Kurabayashi S, Nawano M, Ohashi R, Procter MJ, Qiu L, Rasamison CM, Schofield KL, Shah VK, Ueta K, Williams GM, Witter D, Yasuda K. Castelhano AL, et al. Among authors: procter mj. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1501-4. doi: 10.1016/j.bmcl.2004.12.083. Bioorg Med Chem Lett. 2005. PMID: 15713416
Trastuzumab-associated cardiac events at 8 years of median follow-up in the Herceptin Adjuvant trial (BIG 1-01).
de Azambuja E, Procter MJ, van Veldhuisen DJ, Agbor-Tarh D, Metzger-Filho O, Steinseifer J, Untch M, Smith IE, Gianni L, Baselga J, Jackisch C, Cameron DA, Bell R, Leyland-Jones B, Dowsett M, Gelber RD, Piccart-Gebhart MJ, Suter TM. de Azambuja E, et al. Among authors: procter mj. J Clin Oncol. 2014 Jul 10;32(20):2159-65. doi: 10.1200/JCO.2013.53.9288. Epub 2014 Jun 9. J Clin Oncol. 2014. PMID: 24912899 Clinical Trial.