Garcia ML - Search Results

1

Revealing the molecular determinants of neurotoxin specificity for calcium-activated versus voltage-dependent potassium channels.

Giangiacomo KM, Becker J, Garsky C, Felix JP, Priest BT, Schmalhofer W, Garcia ML, Mullmann TJ. Giangiacomo KM, et al. Among authors: garcia ml. Biochemistry. 2007 May 8;46(18):5358-64. doi: 10.1021/bi700150t. Epub 2007 Apr 18. Biochemistry. 2007. PMID: 17439246

2

Novel alpha-KTx sites in the BK channel and comparative sequence analysis reveal distinguishing features of the BK and KV channel outer pore.

Giangiacomo KM, Becker J, Garsky C, Schmalhofer W, Garcia ML, Mullmann TJ. Giangiacomo KM, et al. Among authors: garcia ml. Cell Biochem Biophys. 2008;52(1):47-58. doi: 10.1007/s12013-008-9026-3. Epub 2008 Sep 25. Cell Biochem Biophys. 2008. PMID: 18815746

3

Glycine 30 in iberiotoxin is a critical determinant of its specificity for maxi-K versus K(V) channels.

Schroeder N, Mullmann TJ, Schmalhofer WA, Gao YD, Garcia ML, Giangiacomo KM. Schroeder N, et al. Among authors: garcia ml. FEBS Lett. 2002 Sep 11;527(1-3):298-302. doi: 10.1016/s0014-5793(02)03256-8. FEBS Lett. 2002. PMID: 12220678 Free article.

4

Mechanism of iberiotoxin block of the large-conductance calcium-activated potassium channel from bovine aortic smooth muscle.

Giangiacomo KM, Garcia ML, McManus OB. Giangiacomo KM, et al. Among authors: garcia ml. Biochemistry. 1992 Jul 28;31(29):6719-27. doi: 10.1021/bi00144a011. Biochemistry. 1992. PMID: 1379069

5

Functional reconstitution of the large-conductance, calcium-activated potassium channel purified from bovine aortic smooth muscle.

Giangiacomo KM, Garcia-Calvo M, Knaus HG, Mullmann TJ, Garcia ML, McManus O. Giangiacomo KM, et al. Among authors: garcia ml, garcia calvo m. Biochemistry. 1995 Dec 5;34(48):15849-62. doi: 10.1021/bi00048a031. Biochemistry. 1995. PMID: 7495817

6

Synthetic charybdotoxin-iberiotoxin chimeric peptides define toxin binding sites on calcium-activated and voltage-dependent potassium channels.

Giangiacomo KM, Sugg EE, Garcia-Calvo M, Leonard RJ, McManus OB, Kaczorowski GJ, Garcia ML. Giangiacomo KM, et al. Among authors: garcia ml, garcia calvo m. Biochemistry. 1993 Mar 9;32(9):2363-70. doi: 10.1021/bi00060a030. Biochemistry. 1993. PMID: 7680230

7

An activator of calcium-dependent potassium channels isolated from a medicinal herb.

McManus OB, Harris GH, Giangiacomo KM, Feigenbaum P, Reuben JP, Addy ME, Burka JF, Kaczorowski GJ, Garcia ML. McManus OB, et al. Among authors: garcia ml. Biochemistry. 1993 Jun 22;32(24):6128-33. doi: 10.1021/bi00075a002. Biochemistry. 1993. PMID: 7685635

8

Electrostatic mutations in iberiotoxin as a unique tool for probing the electrostatic structure of the maxi-K channel outer vestibule.

Mullmann TJ, Munujos P, Garcia ML, Giangiacomo KM. Mullmann TJ, et al. Among authors: garcia ml. Biochemistry. 1999 Feb 23;38(8):2395-402. doi: 10.1021/bi982040+. Biochemistry. 1999. PMID: 10029533

9

Interaction of charybdotoxin S10A with single maxi-K channels: kinetics of blockade depend on the presence of the beta 1 subunit.

Giangiacomo KM, Fremont V, Mullmann TJ, Hanner M, Cox RH, Garcia ML. Giangiacomo KM, et al. Among authors: garcia ml. Biochemistry. 2000 May 23;39(20):6115-22. doi: 10.1021/bi992865z. Biochemistry. 2000. PMID: 10821684

10

A disubstituted succinamide is a potent sodium channel blocker with efficacy in a rat pain model.

Priest BT, Garcia ML, Middleton RE, Brochu RM, Clark S, Dai G, Dick IE, Felix JP, Liu CJ, Reiseter BS, Schmalhofer WA, Shao PP, Tang YS, Chou MZ, Kohler MG, Smith MM, Warren VA, Williams BS, Cohen CJ, Martin WJ, Meinke PT, Parsons WH, Wafford KA, Kaczorowski GJ. Priest BT, et al. Among authors: garcia ml. Biochemistry. 2004 Aug 3;43(30):9866-76. doi: 10.1021/bi0493259. Biochemistry. 2004. PMID: 15274641

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