Irving MB - Search Results

1

Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies.

Saphire EO, Montero M, Menendez A, van Houten NE, Irving MB, Pantophlet R, Zwick MB, Parren PW, Burton DR, Scott JK, Wilson IA. Saphire EO, et al. Among authors: irving mb. J Mol Biol. 2007 Jun 8;369(3):696-709. doi: 10.1016/j.jmb.2007.01.060. Epub 2007 Jan 27. J Mol Biol. 2007. PMID: 17445828 Free PMC article.

2

Exploring peptide mimics for the production of antibodies against discontinuous protein epitopes.

Irving MB, Craig L, Menendez A, Gangadhar BP, Montero M, van Houten NE, Scott JK. Irving MB, et al. Mol Immunol. 2010 Feb;47(5):1137-48. doi: 10.1016/j.molimm.2009.10.015. Epub 2009 Dec 23. Mol Immunol. 2010. PMID: 20031219 Free PMC article.

3

Identification and characterization of a peptide that specifically binds the human, broadly neutralizing anti-human immunodeficiency virus type 1 antibody b12.

Zwick MB, Bonnycastle LL, Menendez A, Irving MB, Barbas CF 3rd, Parren PW, Burton DR, Scott JK. Zwick MB, et al. Among authors: irving mb. J Virol. 2001 Jul;75(14):6692-9. doi: 10.1128/JVI.75.14.6692-6699.2001. J Virol. 2001. PMID: 11413337 Free PMC article.

4

Random-peptide libraries and antigen-fragment libraries for epitope mapping and the development of vaccines and diagnostics.

Irving MB, Pan O, Scott JK. Irving MB, et al. Curr Opin Chem Biol. 2001 Jun;5(3):314-24. doi: 10.1016/s1367-5931(00)00208-8. Curr Opin Chem Biol. 2001. PMID: 11479124 Free PMC article. Review.

5

Preclinical Evaluation and Dosimetry of [¹¹¹In]CHX-DTPA-scFv78-Fc Targeting Endosialin/Tumor Endothelial Marker 1 (TEM1).

Cicone F, Denoël T, Gnesin S, Riggi N, Irving M, Jakka G, Schaefer N, Viertl D, Coukos G, Prior JO. Cicone F, et al. Mol Imaging Biol. 2020 Aug;22(4):979-991. doi: 10.1007/s11307-020-01479-8. Mol Imaging Biol. 2020. PMID: 31993928 Free PMC article.

6

CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8⁺ T-cell Responses.

Liu Y, Cuendet MA, Goffin L, Šachl R, Cebecauer M, Cariolato L, Guillaume P, Reichenbach P, Irving M, Coukos G, Luescher IF. Liu Y, et al. J Mol Biol. 2019 Dec 6;431(24):4941-4958. doi: 10.1016/j.jmb.2019.10.019. Epub 2019 Nov 5. J Mol Biol. 2019. PMID: 31704286 Free article.

7

The T-Cell Receptor Can Bind to the Peptide-Bound Major Histocompatibility Complex and Uncomplexed β₂-Microglobulin through Distinct Binding Sites.

Merkle PS, Irving M, Hongjian S, Ferber M, Jørgensen TJD, Scholten K, Luescher I, Coukos G, Zoete V, Cuendet MA, Michielin O, Rand KD. Merkle PS, et al. Biochemistry. 2017 Aug 1;56(30):3945-3961. doi: 10.1021/acs.biochem.7b00385. Epub 2017 Jul 19. Biochemistry. 2017. PMID: 28671821

8

Reversible major histocompatibility complex I-peptide multimers containing Ni(2+)-nitrilotriacetic acid peptides and histidine tags improve analysis and sorting of CD8(+) T cells.

Schmidt J, Guillaume P, Irving M, Baumgaertner P, Speiser D, Luescher IF. Schmidt J, et al. J Biol Chem. 2011 Dec 2;286(48):41723-41735. doi: 10.1074/jbc.M111.283127. Epub 2011 Oct 11. J Biol Chem. 2011. PMID: 21990358 Free PMC article.

9

Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness.

Irving M, Zoete V, Hebeisen M, Schmid D, Baumgartner P, Guillaume P, Romero P, Speiser D, Luescher I, Rufer N, Michielin O. Irving M, et al. J Biol Chem. 2012 Jun 29;287(27):23068-78. doi: 10.1074/jbc.M112.357673. Epub 2012 May 1. J Biol Chem. 2012. PMID: 22549784 Free PMC article.

10

Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry.

Merkle PS, Trabjerg E, Hongjian S, Ferber M, Cuendet MA, Jørgensen TJD, Luescher I, Irving M, Zoete V, Michielin O, Rand KD. Merkle PS, et al. Biochemistry. 2021 Mar 23;60(11):859-872. doi: 10.1021/acs.biochem.1c00035. Epub 2021 Mar 9. Biochemistry. 2021. PMID: 33689297

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