Lu H - Search Results

1

Structure-based identification of small molecule compounds targeting cell cyclophilin A with anti-HIV-1 activity.

Chen S, Zhao X, Tan J, Lu H, Qi Z, Huang Q, Zeng X, Zhang M, Jiang S, Jiang H, Yu L. Chen S, et al. Among authors: lu h. Eur J Pharmacol. 2007 Jun 22;565(1-3):54-9. doi: 10.1016/j.ejphar.2007.03.023. Epub 2007 Mar 24. Eur J Pharmacol. 2007. PMID: 17449029 Free PMC article.

2

Discovery of a potent peptidic cyclophilin A inhibitor Trp-Gly-Pro.

Pang X, Zhang M, Zhou L, Xie F, Lu H, He W, Jiang S, Yu L, Zhang X. Pang X, et al. Among authors: lu h. Eur J Med Chem. 2011 May;46(5):1701-5. doi: 10.1016/j.ejmech.2011.02.023. Epub 2011 Feb 22. Eur J Med Chem. 2011. PMID: 21396746

3

Structure-based design, synthesis and biological evaluation of new N-carboxyphenylpyrrole derivatives as HIV fusion inhibitors targeting gp41.

Wang Y, Lu H, Zhu Q, Jiang S, Liao Y. Wang Y, et al. Among authors: lu h. Bioorg Med Chem Lett. 2010 Jan 1;20(1):189-92. doi: 10.1016/j.bmcl.2009.10.139. Epub 2009 Nov 5. Bioorg Med Chem Lett. 2010. PMID: 19932616 Free PMC article.

4

Novel recombinant engineered gp41 N-terminal heptad repeat trimers and their potential as anti-HIV-1 therapeutics or microbicides.

Chen X, Lu L, Qi Z, Lu H, Wang J, Yu X, Chen Y, Jiang S. Chen X, et al. Among authors: lu h, lu l. J Biol Chem. 2010 Aug 13;285(33):25506-15. doi: 10.1074/jbc.M110.101170. Epub 2010 Jun 10. J Biol Chem. 2010. PMID: 20538590 Free PMC article.

5

A bivalent recombinant protein inactivates HIV-1 by targeting the gp41 prehairpin fusion intermediate induced by CD4 D1D2 domains.

Lu L, Pan C, Li Y, Lu H, He W, Jiang S. Lu L, et al. Among authors: lu h. Retrovirology. 2012 Dec 7;9:104. doi: 10.1186/1742-4690-9-104. Retrovirology. 2012. PMID: 23217195 Free PMC article.

6

Identification of a critical motif for the human immunodeficiency virus type 1 (HIV-1) gp41 core structure: implications for designing novel anti-HIV fusion inhibitors.

He Y, Cheng J, Li J, Qi Z, Lu H, Dong M, Jiang S, Dai Q. He Y, et al. Among authors: lu h. J Virol. 2008 Jul;82(13):6349-58. doi: 10.1128/JVI.00319-08. Epub 2008 Apr 16. J Virol. 2008. PMID: 18417584 Free PMC article.

7

ADS-J1 inhibits human immunodeficiency virus type 1 entry by interacting with the gp41 pocket region and blocking fusion-active gp41 core formation.

Wang H, Qi Z, Guo A, Mao Q, Lu H, An X, Xia C, Li X, Debnath AK, Wu S, Liu S, Jiang S. Wang H, et al. Among authors: lu h. Antimicrob Agents Chemother. 2009 Dec;53(12):4987-98. doi: 10.1128/AAC.00670-09. Epub 2009 Sep 28. Antimicrob Agents Chemother. 2009. PMID: 19786602 Free PMC article.

8

Design, synthesis, and biological evaluation of N-carboxyphenylpyrrole derivatives as potent HIV fusion inhibitors targeting gp41.

Liu K, Lu H, Hou L, Qi Z, Teixeira C, Barbault F, Fan BT, Liu S, Jiang S, Xie L. Liu K, et al. Among authors: lu h. J Med Chem. 2008 Dec 25;51(24):7843-54. doi: 10.1021/jm800869t. J Med Chem. 2008. PMID: 19053778 Free PMC article.

9

Synergistic efficacy of combination of enfuvirtide and sifuvirtide, the first- and next-generation HIV-fusion inhibitors.

Pan C, Lu H, Qi Z, Jiang S. Pan C, et al. Among authors: lu h. AIDS. 2009 Mar 13;23(5):639-41. doi: 10.1097/QAD.0b013e328325a4cd. AIDS. 2009. PMID: 19242316 Free PMC article.

10

Combinations of the first and next generations of human immunodeficiency virus (HIV) fusion inhibitors exhibit a highly potent synergistic effect against enfuvirtide- sensitive and -resistant HIV type 1 strains.

Pan C, Cai L, Lu H, Qi Z, Jiang S. Pan C, et al. Among authors: lu h. J Virol. 2009 Aug;83(16):7862-72. doi: 10.1128/JVI.00168-09. Epub 2009 Jun 3. J Virol. 2009. PMID: 19493996 Free PMC article.

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