Herschhorn A - Search Results

1

De novo parallel design, synthesis and evaluation of inhibitors against the reverse transcriptase of human immunodeficiency virus type-1 and drug-resistant variants.

Herschhorn A, Lerman L, Weitman M, Gleenberg IO, Nudelman A, Hizi A. Herschhorn A, et al. J Med Chem. 2007 May 17;50(10):2370-84. doi: 10.1021/jm0613121. Epub 2007 Apr 26. J Med Chem. 2007. PMID: 17458947

2

Recombinant human antibodies against the reverse transcriptase of human immunodeficiency virus type-1.

Herschhorn A, Admon A, Hizi A. Herschhorn A, et al. Biochim Biophys Acta. 2003 May 30;1648(1-2):154-63. doi: 10.1016/s1570-9639(03)00118-3. Biochim Biophys Acta. 2003. PMID: 12758158

3

Peptides derived from the reverse transcriptase of human immunodeficiency virus type 1 as novel inhibitors of the viral integrase.

Oz Gleenberg I, Avidan O, Goldgur Y, Herschhorn A, Hizi A. Oz Gleenberg I, et al. Among authors: herschhorn a. J Biol Chem. 2005 Jun 10;280(23):21987-96. doi: 10.1074/jbc.M414679200. Epub 2005 Mar 23. J Biol Chem. 2005. PMID: 15790559 Free article.

4

Inhibition of human immunodeficiency virus type-1 reverse transcriptase by a novel peptide derived from the viral integrase.

Oz Gleenberg I, Herschhorn A, Goldgur Y, Hizi A. Oz Gleenberg I, et al. Among authors: herschhorn a. Arch Biochem Biophys. 2007 Feb 15;458(2):202-12. doi: 10.1016/j.abb.2006.12.007. Epub 2006 Dec 28. Arch Biochem Biophys. 2007. PMID: 17257575

5

Inhibition of the activities of reverse transcriptase and integrase of human immunodeficiency virus type-1 by peptides derived from the homologous viral protein R (Vpr).

Gleenberg IO, Herschhorn A, Hizi A. Gleenberg IO, et al. Among authors: herschhorn a. J Mol Biol. 2007 Jun 22;369(5):1230-43. doi: 10.1016/j.jmb.2007.03.073. Epub 2007 Apr 1. J Mol Biol. 2007. PMID: 17490682

6

Mechanism of inhibition of HIV-1 reverse transcriptase by the novel broad-range DNA polymerase inhibitor N-{2-[4-(aminosulfonyl)phenyl]ethyl}-2-(2-thienyl)acetamide.

Herschhorn A, Oz-Gleenberg I, Hizi A. Herschhorn A, et al. Biochemistry. 2008 Jan 8;47(1):490-502. doi: 10.1021/bi7018139. Epub 2007 Dec 5. Biochemistry. 2008. PMID: 18052256

7

Retroviral reverse transcriptases (other than those of HIV-1 and murine leukemia virus): a comparison of their molecular and biochemical properties.

Hizi A, Herschhorn A. Hizi A, et al. Among authors: herschhorn a. Virus Res. 2008 Jun;134(1-2):203-20. doi: 10.1016/j.virusres.2007.12.008. Epub 2008 Mar 3. Virus Res. 2008. PMID: 18291546 Review.

8

Virtual screening, identification, and biochemical characterization of novel inhibitors of the reverse transcriptase of human immunodeficiency virus type-1.

Herschhorn A, Hizi A. Herschhorn A, et al. J Med Chem. 2008 Sep 25;51(18):5702-13. doi: 10.1021/jm800473d. J Med Chem. 2008. PMID: 18800765

9

Retroviral reverse transcriptases.

Herschhorn A, Hizi A. Herschhorn A, et al. Cell Mol Life Sci. 2010 Aug;67(16):2717-47. doi: 10.1007/s00018-010-0346-2. Epub 2010 Apr 1. Cell Mol Life Sci. 2010. PMID: 20358252 Free PMC article. Review.

10

Reverse transcriptases can clamp together nucleic acids strands with two complementary bases at their 3'-termini for initiating DNA synthesis.

Oz-Gleenberg I, Herschhorn A, Hizi A. Oz-Gleenberg I, et al. Among authors: herschhorn a. Nucleic Acids Res. 2011 Feb;39(3):1042-53. doi: 10.1093/nar/gkq786. Epub 2010 Sep 28. Nucleic Acids Res. 2011. PMID: 20876692 Free PMC article.

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