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A novel valproic acid prodrug as an anticancer agent that enhances doxorubicin anticancer activity and protects normal cells against its toxicity in vitro and in vivo.
Tarasenko N, Cutts SM, Phillips DR, Berkovitch-Luria G, Bardugo-Nissim E, Weitman M, Nudelman A, Rephaeli A. Tarasenko N, et al. Among authors: weitman m. Biochem Pharmacol. 2014 Mar 15;88(2):158-68. doi: 10.1016/j.bcp.2014.01.023. Epub 2014 Jan 24. Biochem Pharmacol. 2014. PMID: 24463168
Synthesis and in vitro evaluation of anti-inflammatory activity of ester and amine derivatives of indoline in RAW 264.7 and peritoneal macrophages.
Furman S, Nissim-Bardugo E, Zeeli S, Weitman M, Nudelman A, Finkin-Groner E, Moradov D, Shifrin H, Schorer-Apelbaum D, Weinstock M. Furman S, et al. Among authors: weitman m. Bioorg Med Chem Lett. 2014 May 15;24(10):2283-7. doi: 10.1016/j.bmcl.2014.03.081. Epub 2014 Apr 2. Bioorg Med Chem Lett. 2014. PMID: 24731278
The Therapeutic Potential of AN-7, a Novel Histone Deacetylase Inhibitor, for Treatment of Mycosis Fungoides/Sezary Syndrome Alone or with Doxorubicin.
Moyal L, Feldbaum N, Goldfeiz N, Rephaeli A, Nudelman A, Weitman M, Tarasenko N, Gorovitz B, Maron L, Yehezkel S, Amitay-Laish I, Lubin I, Hodak E. Moyal L, et al. Among authors: weitman m. PLoS One. 2016 Jan 11;11(1):e0146115. doi: 10.1371/journal.pone.0146115. eCollection 2016. PLoS One. 2016. PMID: 26752418 Free PMC article.
Structurally Simple, Readily Available Peptidomimetic 1-Benzyl-5-methyl-4-( n-octylamino)pyrimidin-2(1 H)-one Exhibited Efficient Cardioprotection in a Myocardial Ischemia (MI) Mouse Model.
Trifonov L, Nudelman V, Zhenin M, Matsree E, Afri M, Schmerling B, Cohen G, Jozwiak K, Weitman M, Korshin E, Senderowitz H, Shainberg A, Hochhauser E, Gruzman A. Trifonov L, et al. Among authors: weitman m. J Med Chem. 2018 Dec 27;61(24):11309-11326. doi: 10.1021/acs.jmedchem.8b01471. Epub 2018 Dec 11. J Med Chem. 2018. PMID: 30507195
50 results