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Spirolactone iridoids might be responsible for the antileishmanial activity of a Peruvian traditional remedy made with Himatanthus sucuuba (Apocynaceae).
Castillo D, Arevalo J, Herrera F, Ruiz C, Rojas R, Rengifo E, Vaisberg A, Lock O, Lemesre JL, Gornitzka H, Sauvain M. Castillo D, et al. Among authors: lock o. J Ethnopharmacol. 2007 Jun 13;112(2):410-4. doi: 10.1016/j.jep.2007.03.025. Epub 2007 Mar 24. J Ethnopharmacol. 2007. PMID: 17459622 Free article.
Antimicrobial activity of selected Peruvian medicinal plants.
Rojas R, Bustamante B, Bauer J, Fernández I, Albán J, Lock O. Rojas R, et al. Among authors: lock o. J Ethnopharmacol. 2003 Oct;88(2-3):199-204. doi: 10.1016/s0378-8741(03)00212-5. J Ethnopharmacol. 2003. PMID: 12963143
A U.S. Pharmacopeia (USP) overview of Pan American botanicals used in dietary supplements and herbal medicines.
Upton R, Agudelo I, Cabrera Y, Caceres A, Calderón A, Calzada F, Camacho R, da Costa F, Dobrecky C, Enciso R, Escobar M, Fakhary M, Fletcher E, Gao Q, Lock O, Mata R, Parada M, Perera W, Pombo LM, Reich E, Sanchez E, Simirgiotis MJ, Sood C, Amiguet VT, Villar M, Ghelman R, Schveitzer MC, Portella CFS, Wolffenbüttel A, Ruppelt B, Frickmann FS, Gavillan-Suarez J, Allen K, Alvarado LD, Sarma N, Marles R, Monagas M, Navarro-Hoyos M. Upton R, et al. Among authors: lock o. Front Pharmacol. 2024 Aug 30;15:1426210. doi: 10.3389/fphar.2024.1426210. eCollection 2024. Front Pharmacol. 2024. PMID: 39281273 Free PMC article. Review.
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