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A specific chymase inhibitor, 2-(5-formylamino-6-oxo-2-phenyl-1,6-dihydropyrimidine-1-yl)-N-[[3,4-dioxo-1-phenyl-7-(2-pyridyloxy)]-2-heptyl]acetamide (NK3201), suppresses development of abdominal aortic aneurysm in hamsters.
Tsunemi K, Takai S, Nishimoto M, Jin D, Sakaguchi M, Muramatsu M, Yuda A, Sasaki S, Miyazaki M. Tsunemi K, et al. Among authors: muramatsu m. J Pharmacol Exp Ther. 2004 Jun;309(3):879-83. doi: 10.1124/jpet.103.063974. Epub 2004 Feb 11. J Pharmacol Exp Ther. 2004. PMID: 14960660
Effect of chymase inhibition on the arteriovenous fistula stenosis in dogs.
Jin D, Ueda H, Takai S, Okamoto Y, Muramatsu M, Sakaguchi M, Shibahara N, Katsuoka Y, Miyazaki M. Jin D, et al. Among authors: muramatsu m. J Am Soc Nephrol. 2005 Apr;16(4):1024-34. doi: 10.1681/ASN.2003121009. Epub 2005 Mar 2. J Am Soc Nephrol. 2005. PMID: 15744002
1,396 results