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Page 1
Discovery of new C3aR ligands. Part 1: arginine derivatives.
Denonne F, Binet S, Burton M, Collart P, Dipesa A, Ganguly T, Giannaras A, Kumar S, Lewis T, Maounis F, Nicolas JM, Mansley T, Pasau P, Preda D, Stebbins K, Volosov A, Zou D. Denonne F, et al. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3258-61. doi: 10.1016/j.bmcl.2007.04.022. Epub 2007 Apr 10. Bioorg Med Chem Lett. 2007. PMID: 17467987
Discovery of new C3aR ligands. Part 2: amino-piperidine derivatives.
Denonne F, Binet S, Burton M, Collart P, Defays S, Dipesa A, Eckert M, Giannaras A, Kumar S, Levine B, Nicolas JM, Pasau P, Pégurier C, Preda D, Van houtvin N, Volosov A, Zou D. Denonne F, et al. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3262-5. doi: 10.1016/j.bmcl.2007.04.023. Epub 2007 Apr 10. Bioorg Med Chem Lett. 2007. PMID: 17459702
Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists.
Célanire S, Wijtmans M, Christophe B, Collart P, de Esch I, Dassesse D, Delaunoy C, Denonne F, Durieu V, Gelens E, Gillard M, Lallemand B, Lamberty Y, Lebon F, Nicolas JM, Quéré L, Snip E, Vanbellinghen A, Van Houtvin N, Verbois V, Timmerman H, Talaga P, Leurs R, Provins L. Célanire S, et al. Among authors: denonne f. ChemMedChem. 2009 Jul;4(7):1063-8. doi: 10.1002/cmdc.200900055. ChemMedChem. 2009. PMID: 19405064
Acetamide scanning around bicyclic thiazoles: SAR at the H₃ receptor.
Denonne F, Célanire S, Christophe B, Defays S, Delaunoy C, Delporte ML, Detrait E, Durieu V, Gillard M, Lamberty Y, Lorent G, Nicolas JM, Vanbellinghen A, Van Houtvin N, Provins L. Denonne F, et al. ChemMedChem. 2011 Sep 5;6(9):1559-65. doi: 10.1002/cmdc.201100248. Epub 2011 Jul 14. ChemMedChem. 2011. PMID: 21761567 No abstract available.
8-Substituted 1,3-dimethyltetrahydropyrazino[2,1-f]purinediones: Water-soluble adenosine receptor antagonists and monoamine oxidase B inhibitors.
Brunschweiger A, Koch P, Schlenk M, Rafehi M, Radjainia H, Küppers P, Hinz S, Pineda F, Wiese M, Hockemeyer J, Heer J, Denonne F, Müller CE. Brunschweiger A, et al. Among authors: denonne f. Bioorg Med Chem. 2016 Nov 1;24(21):5462-5480. doi: 10.1016/j.bmc.2016.09.003. Epub 2016 Sep 3. Bioorg Med Chem. 2016. PMID: 27658798
GPCRs in medicinal chemistry.
Denonne F. Denonne F. IDrugs. 2008 Dec;11(12):870-5. IDrugs. 2008. PMID: 19051146 No abstract available.
Phenyl-oxazoles, a new family of inverse agonists at the H(3) histamine receptor.
Denonne F, Atienzar F, Célanire S, Christophe B, Delannois F, Delaunoy C, Delporte ML, Durieu V, Gillard M, Lallemand B, Lamberty Y, Lorent G, Vanbellinghen A, Van Houtvin N, Verbois V, Provins L. Denonne F, et al. ChemMedChem. 2010 Feb 1;5(2):206-12. doi: 10.1002/cmdc.200900446. ChemMedChem. 2010. PMID: 20043314 No abstract available.
Lead optimization of thiazolo[5,4-c]piperidines: 3-cyclobutoxy linker as a key spacer for H(3)R inverse agonists.
Provins L, Denonne F, Célanire S, Christophe B, Defays S, Delaunoy C, Delporte ML, Demaude T, Durieu V, Gillard M, Hubert D, Lamberty Y, Lorent G, Valade A, Vanbellinghen A, Van Houtvin N. Provins L, et al. Among authors: denonne f. ChemMedChem. 2012 Dec;7(12):2087-92. doi: 10.1002/cmdc.201200406. Epub 2012 Oct 5. ChemMedChem. 2012. PMID: 23042668