Spehlmann ME - Search Results

1

Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial.

Targan SR, Feagan BG, Fedorak RN, Lashner BA, Panaccione R, Present DH, Spehlmann ME, Rutgeerts PJ, Tulassay Z, Volfova M, Wolf DC, Hernandez C, Bornstein J, Sandborn WJ; International Efficacy of Natalizumab in Crohn's Disease Response and Remission (ENCORE) Trial Group. Targan SR, et al. Among authors: spehlmann me. Gastroenterology. 2007 May;132(5):1672-83. doi: 10.1053/j.gastro.2007.03.024. Epub 2007 Mar 21. Gastroenterology. 2007. PMID: 17484865 Clinical Trial.

2

Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab.

Sandborn WJ, Abreu MT, D'Haens G, Colombel JF, Vermeire S, Mitchev K, Jamoul C, Fedorak RN, Spehlmann ME, Wolf DC, Lee S, Rutgeerts P. Sandborn WJ, et al. Among authors: spehlmann me. Clin Gastroenterol Hepatol. 2010 Aug;8(8):688-695.e2. doi: 10.1016/j.cgh.2010.04.021. Epub 2010 May 6. Clin Gastroenterol Hepatol. 2010. PMID: 20451663 Clinical Trial.

3

Interferon-beta-1a for the treatment of steroid-refractory ulcerative colitis: a randomized, double-blind, placebo-controlled trial.

Musch E, Andus T, Kruis W, Raedler A, Spehlmann M, Schreiber S, Krakamp B, Malek M, Malchow H, Zavada F, Engelberg Feurle G. Musch E, et al. Clin Gastroenterol Hepatol. 2005 Jun;3(6):581-6. doi: 10.1016/s1542-3565(05)00208-9. Clin Gastroenterol Hepatol. 2005. PMID: 15952100 Clinical Trial.

4

Nuclear factor-kappa B in intestinal protection and destruction.

Spehlmann ME, Eckmann L. Spehlmann ME, et al. Curr Opin Gastroenterol. 2009 Mar;25(2):92-9. doi: 10.1097/MOG.0b013e328324f857. Curr Opin Gastroenterol. 2009. PMID: 19528876 Review.

5

Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis.

Lepage P, Häsler R, Spehlmann ME, Rehman A, Zvirbliene A, Begun A, Ott S, Kupcinskas L, Doré J, Raedler A, Schreiber S. Lepage P, et al. Among authors: spehlmann me. Gastroenterology. 2011 Jul;141(1):227-36. doi: 10.1053/j.gastro.2011.04.011. Epub 2011 Apr 16. Gastroenterology. 2011. PMID: 21621540

6

Combined alpha-methylacyl coenzyme A racemase/p53 analysis to identify dysplasia in inflammatory bowel disease.

Marx A, Wandrey T, Simon P, Wewer A, Grob T, Reichelt U, Minner S, Simon R, Spehlmann M, Tigges W, Soehendra N, Seitz U, Seewald S, Izbicki JR, Yekebas E, Kaifi JT, Mirlacher M, Terracciano L, Fleischmann A, Raedler A, Sauter G. Marx A, et al. Hum Pathol. 2009 Feb;40(2):166-73. doi: 10.1016/j.humpath.2008.06.027. Epub 2008 Oct 5. Hum Pathol. 2009. PMID: 18835622

7

Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation.

Guma M, Stepniak D, Shaked H, Spehlmann ME, Shenouda S, Cheroutre H, Vicente-Suarez I, Eckmann L, Kagnoff MF, Karin M. Guma M, et al. Among authors: spehlmann me. J Exp Med. 2011 Aug 29;208(9):1889-900. doi: 10.1084/jem.20110242. Epub 2011 Aug 8. J Exp Med. 2011. PMID: 21825016 Free PMC article.

8

IL-6-dependent mucosal protection prevents establishment of a microbial niche for attaching/effacing lesion-forming enteric bacterial pathogens.

Dann SM, Spehlmann ME, Hammond DC, Iimura M, Hase K, Choi LJ, Hanson E, Eckmann L. Dann SM, et al. Among authors: spehlmann me. J Immunol. 2008 May 15;180(10):6816-26. doi: 10.4049/jimmunol.180.10.6816. J Immunol. 2008. PMID: 18453602 Free PMC article.

9

CXCR2-dependent mucosal neutrophil influx protects against colitis-associated diarrhea caused by an attaching/effacing lesion-forming bacterial pathogen.

Spehlmann ME, Dann SM, Hruz P, Hanson E, McCole DF, Eckmann L. Spehlmann ME, et al. J Immunol. 2009 Sep 1;183(5):3332-43. doi: 10.4049/jimmunol.0900600. Epub 2009 Aug 12. J Immunol. 2009. PMID: 19675161 Free PMC article.

10

Coordinate down-regulation of adenylyl cyclase isoforms and the stimulatory G protein (G(s)) in intestinal epithelial cell differentiation.

Choi LJ, Jenikova G, Hanson E, Spehlmann ME, Boehling NS, Kirstein SL, Bundey RA, Smith JR, Insel PA, Eckmann L. Choi LJ, et al. Among authors: spehlmann me. J Biol Chem. 2010 Apr 23;285(17):12504-11. doi: 10.1074/jbc.M109.059741. Epub 2010 Feb 15. J Biol Chem. 2010. PMID: 20157112 Free PMC article.

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