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The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury.
Deng W, Shuyu E, Tsukahara R, Valentine WJ, Durgam G, Gududuru V, Balazs L, Manickam V, Arsura M, VanMiddlesworth L, Johnson LR, Parrill AL, Miller DD, Tigyi G. Deng W, et al. Among authors: johnson lr. Gastroenterology. 2007 May;132(5):1834-51. doi: 10.1053/j.gastro.2007.03.038. Epub 2007 Mar 24. Gastroenterology. 2007. PMID: 17484878 Free PMC article.
Polyamine depletion inhibits irradiation-induced apoptosis in intestinal epithelia.
Deng W, Viar MJ, Johnson LR. Deng W, et al. Among authors: johnson lr. Am J Physiol Gastrointest Liver Physiol. 2005 Sep;289(3):G599-606. doi: 10.1152/ajpgi.00564.2004. Epub 2005 Apr 28. Am J Physiol Gastrointest Liver Physiol. 2005. PMID: 15860639 Free article.
Our group has previously shown that polyamine depletion delays apoptosis in rat intestinal epithelial (IEC-6) cells (Ray RM, Viar MJ, Yuan Q, and Johnson LR, Am J Physiol Cell Physiol 278: C480-C489, 2000). Here, we demonstrate that polyamine depletion inhibits gamm …
Our group has previously shown that polyamine depletion delays apoptosis in rat intestinal epithelial (IEC-6) cells (Ray RM, Viar MJ, Yuan Q …
Lysophosphatidic acid induces neointima formation through PPARgamma activation.
Zhang C, Baker DL, Yasuda S, Makarova N, Balazs L, Johnson LR, Marathe GK, McIntyre TM, Xu Y, Prestwich GD, Byun HS, Bittman R, Tigyi G. Zhang C, et al. Among authors: johnson lr. J Exp Med. 2004 Mar 15;199(6):763-74. doi: 10.1084/jem.20031619. Epub 2004 Mar 8. J Exp Med. 2004. PMID: 15007093 Free PMC article.
Mitigation of the hematopoietic and gastrointestinal acute radiation syndrome by octadecenyl thiophosphate, a small molecule mimic of lysophosphatidic acid.
Deng W, Kimura Y, Gududuru V, Wu W, Balogh A, Szabo E, Thompson KE, Yates CR, Balazs L, Johnson LR, Miller DD, Strobos J, McCool WS, Tigyi GJ. Deng W, et al. Among authors: johnson lr. Radiat Res. 2015 Apr;183(4):465-75. doi: 10.1667/RR13830.1. Epub 2015 Mar 25. Radiat Res. 2015. PMID: 25807318 Free PMC article.
Prevention and treatment of secretory diarrhea by the lysophosphatidic acid analog Rx100.
Thompson KE, Ray RM, Alli S, Ge W, Boler A, Shannon McCool W, Meena AS, Shukla PK, Rao R, Johnson LR, Miller MA, Tigyi GJ. Thompson KE, et al. Among authors: johnson lr. Exp Biol Med (Maywood). 2018 Sep;243(13):1056-1065. doi: 10.1177/1535370218803349. Epub 2018 Sep 25. Exp Biol Med (Maywood). 2018. PMID: 30253666 Free PMC article.
641 results