Vasella A - Search Results

1

The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.

Caines ME, Hancock SM, Tarling CA, Wrodnigg TM, Stick RV, Stütz AE, Vasella A, Withers SG, Strynadka NC. Caines ME, et al. Among authors: vasella a. Angew Chem Int Ed Engl. 2007;46(24):4474-6. doi: 10.1002/anie.200700268. Angew Chem Int Ed Engl. 2007. PMID: 17487923 No abstract available.

2

Glycosidase inhibition: an assessment of the binding of 18 putative transition-state mimics.

Gloster TM, Meloncelli P, Stick RV, Zechel D, Vasella A, Davies GJ. Gloster TM, et al. Among authors: vasella a. J Am Chem Soc. 2007 Feb 28;129(8):2345-54. doi: 10.1021/ja066961g. Epub 2007 Feb 6. J Am Chem Soc. 2007. PMID: 17279749

3

Structural and biochemical evidence for a boat-like transition state in beta-mannosidases.

Tailford LE, Offen WA, Smith NL, Dumon C, Morland C, Gratien J, Heck MP, Stick RV, Blériot Y, Vasella A, Gilbert HJ, Davies GJ. Tailford LE, et al. Among authors: vasella a. Nat Chem Biol. 2008 May;4(5):306-12. doi: 10.1038/nchembio.81. Nat Chem Biol. 2008. PMID: 18408714

4

A structural view of the action of Escherichia coli (lacZ) beta-galactosidase.

Juers DH, Heightman TD, Vasella A, McCarter JD, Mackenzie L, Withers SG, Matthews BW. Juers DH, et al. Among authors: vasella a. Biochemistry. 2001 Dec 11;40(49):14781-94. doi: 10.1021/bi011727i. Biochemistry. 2001. PMID: 11732897

5

Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.

Mitchell EP, Withers SG, Ermert P, Vasella AT, Garman EF, Oikonomakos NG, Johnson LN. Mitchell EP, et al. Among authors: vasella at. Biochemistry. 1996 Jun 11;35(23):7341-55. doi: 10.1021/bi960072w. Biochemistry. 1996. PMID: 8652510

6

Glycosidase mechanisms.

Vasella A, Davies GJ, Böhm M. Vasella A, et al. Curr Opin Chem Biol. 2002 Oct;6(5):619-29. doi: 10.1016/s1367-5931(02)00380-0. Curr Opin Chem Biol. 2002. PMID: 12413546 Review.

7

Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors.

Gloster TM, Roberts S, Ducros VM, Perugino G, Rossi M, Hoos R, Moracci M, Vasella A, Davies GJ. Gloster TM, et al. Among authors: vasella a. Biochemistry. 2004 May 25;43(20):6101-9. doi: 10.1021/bi049666m. Biochemistry. 2004. PMID: 15147194

8

Structural, kinetic, and thermodynamic analysis of glucoimidazole-derived glycosidase inhibitors.

Gloster TM, Roberts S, Perugino G, Rossi M, Moracci M, Panday N, Terinek M, Vasella A, Davies GJ. Gloster TM, et al. Among authors: vasella a. Biochemistry. 2006 Oct 3;45(39):11879-84. doi: 10.1021/bi060973x. Biochemistry. 2006. PMID: 17002288

9

Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc-imidazole hybrid inhibitor.

Shanmugasundaram B, Debowski AW, Dennis RJ, Davies GJ, Vocadlo DJ, Vasella A. Shanmugasundaram B, et al. Among authors: vasella a. Chem Commun (Camb). 2006 Nov 13;(42):4372-4. doi: 10.1039/b612154c. Epub 2006 Sep 29. Chem Commun (Camb). 2006. PMID: 17057847

10

Recent Insights into Inhibition, Structure, and Mechanism of Configuration-Retaining Glycosidases.

Heightman TD, Vasella AT. Heightman TD, et al. Angew Chem Int Ed Engl. 1999 Mar 15;38(6):750-770. doi: 10.1002/(SICI)1521-3773(19990315)38:6<750::AID-ANIE750>3.0.CO;2-6. Angew Chem Int Ed Engl. 1999. PMID: 29711789 Review.

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