Wrodnigg TM - Search Results

1

The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.

Caines ME, Hancock SM, Tarling CA, Wrodnigg TM, Stick RV, Stütz AE, Vasella A, Withers SG, Strynadka NC. Caines ME, et al. Among authors: wrodnigg tm. Angew Chem Int Ed Engl. 2007;46(24):4474-6. doi: 10.1002/anie.200700268. Angew Chem Int Ed Engl. 2007. PMID: 17487923 No abstract available.

2

Novel, lipophilic derivatives of 2,5-dideoxy-2,5-imino-D-mannitol (DMDP) are powerful beta-glucosidase inhibitors.

Wrodnigg TM, Withers SG, Stütz AE. Wrodnigg TM, et al. Bioorg Med Chem Lett. 2001 Apr 23;11(8):1063-4. doi: 10.1016/s0960-894x(01)00126-3. Bioorg Med Chem Lett. 2001. PMID: 11327590

3

Powerful probes for glycosidases: novel, fluorescently tagged glycosidase inhibitors.

Hermetter A, Scholze H, Stütz AE, Withers SG, Wrodnigg TM. Hermetter A, et al. Among authors: wrodnigg tm. Bioorg Med Chem Lett. 2001 May 21;11(10):1339-42. doi: 10.1016/s0960-894x(01)00209-8. Bioorg Med Chem Lett. 2001. PMID: 11392550

4

A simple access to the D-mannosidase inhibitor, 1-deoxymannojirimycin.

Spreitz J, Stütz AE, Wrodnigg TM. Spreitz J, et al. Among authors: wrodnigg tm. Carbohydr Res. 2002 Feb 5;337(2):183-6. doi: 10.1016/s0008-6215(01)00291-9. Carbohydr Res. 2002. PMID: 11814451

5

Iminosugars and relatives as antiviral and potential anti-infective agents.

Greimel P, Spreitz J, Stütz AE, Wrodnigg TM. Greimel P, et al. Among authors: wrodnigg tm. Curr Top Med Chem. 2003;3(5):513-23. doi: 10.2174/1568026033452456. Curr Top Med Chem. 2003. PMID: 12570863 Review.

6

Probing the aglycon binding site of a beta-glucosidase: a collection of C-1-modified 2,5-dideoxy-2,5-imino-D-mannitol derivatives and their structure-activity relationships as competitive inhibitors.

Wrodnigg TM, Diness F, Gruber C, Häusler H, Lundt I, Rupitz K, Steiner AJ, Stütz AE, Tarling CA, Withers SG, Wölfler H. Wrodnigg TM, et al. Bioorg Med Chem. 2004 Jul 1;12(13):3485-95. doi: 10.1016/j.bmc.2004.04.037. Bioorg Med Chem. 2004. PMID: 15186833

7

In situ extension as an approach for identifying novel alpha-amylase inhibitors.

Numao S, Damager I, Li C, Wrodnigg TM, Begum A, Overall CM, Brayer GD, Withers SG. Numao S, et al. Among authors: wrodnigg tm. J Biol Chem. 2004 Nov 12;279(46):48282-91. doi: 10.1074/jbc.M406804200. Epub 2004 Aug 10. J Biol Chem. 2004. PMID: 15304511 Free article.

8

Fluorescently tagged iminoalditol glycosidase inhibitors as novel biological probes and diagnostics.

Lundt I, Steiner AJ, Stütz AE, Tarling CA, Ully S, Withers SG, Wrodnigg TM. Lundt I, et al. Among authors: wrodnigg tm. Bioorg Med Chem. 2006 Mar 15;14(6):1737-42. doi: 10.1016/j.bmc.2005.10.021. Epub 2005 Nov 7. Bioorg Med Chem. 2006. PMID: 16274997

9

Fluorescent glycosidase inhibiting 1,5-dideoxy-1,5-iminoalditols.

Greimel P, Häusler H, Lundt I, Rupitz K, Stütz AE, Tarling CA, Withers SG, Wrodnigg TM. Greimel P, et al. Among authors: wrodnigg tm. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2067-70. doi: 10.1016/j.bmcl.2006.01.095. Epub 2006 Feb 14. Bioorg Med Chem Lett. 2006. PMID: 16481162

10

Fine tuning of beta-glucosidase inhibitory activity in the 2,5-dideoxy-2,5-imino-D-mannitol (DMDP) system.

Wrodnigg TM, Stütz AE, Tarling CA, Withers SG. Wrodnigg TM, et al. Carbohydr Res. 2006 Jul 24;341(10):1717-22. doi: 10.1016/j.carres.2006.03.010. Epub 2006 Apr 17. Carbohydr Res. 2006. PMID: 16616905

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