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A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation.
Chapman RW, Minnicozzi M, Celly CS, Phillips JE, Kung TT, Hipkin RW, Fan X, Rindgen D, Deno G, Bond R, Gonsiorek W, Billah MM, Fine JS, Hey JA. Chapman RW, et al. Among authors: kung tt. J Pharmacol Exp Ther. 2007 Aug;322(2):486-93. doi: 10.1124/jpet.106.119040. Epub 2007 May 11. J Pharmacol Exp Ther. 2007. PMID: 17496165
Role of nitric oxide on eosinophilic lung inflammation in allergic mice.
Feder LS, Stelts D, Chapman RW, Manfra D, Crawley Y, Jones H, Minnicozzi M, Fernandez X, Paster T, Egan RW, Kreutner W, Kung TT. Feder LS, et al. Among authors: kung tt. Am J Respir Cell Mol Biol. 1997 Oct;17(4):436-42. doi: 10.1165/ajrcmb.17.4.2845. Am J Respir Cell Mol Biol. 1997. PMID: 9376118
35 results